Chinese Academy of Sciences

Beijing Greatsun Bto-pharm. Tech. Co., Ltd

Beijing Municipal Engineering Research Institute

Beijing Greatsun Bio-pharm. Tech. Co., Ltd

Yue Su

Hao Liu

Ming Liu

Qiang Zhang

Liwen Dong

Ling Li

Nianduan Lu

Di Geng

Jun Yuan

Xun Xi

Guanghua Cui

Shengtao Shi

Hui Fang

Xinling Wang

Changjin Lee

Yafei Bai

Yang Zhou

Cuishuan Wu

Jinglai Sun

A digital twin-based intelligent slope monitoring method, system, and storage medium are provided. The method includes obtaining point cloud data of a surface of a slope, creating a digital twin model; dividing the digital twin model to generate a plurality of first grids, calculating a displacement change value of each first grid during a target duration; defining the first grid with a displacement change value greater than a first threshold as a first region, dividing the target duration into a plurality of first durations with different lengths; setting a plurality of rainfall patterns, determining an optimal pattern for each first duration, calculating representative rainfall, constructing a prediction model, predicting representative rainfall for a future duration based on the optimal pattern and the representative rainfall of the first duration; generating a safety factor of the first region during the future duration based on the representative rainfall and a pore water pressure.

Digital twin-based intelligent slope monitoring methods, systems, and storage media

A pixel compensation circuit including a first transistor, a second transistor, a third transistor, a fourth transistor, a fifth transistor, a sixth transistor, a first capacitor, a second capacitor, and an organic light-emitting diode, each of the first transistor to the sixth transistor including a drain, a source and a gate.

Pixel compensation circuit

The present invention relates to a long-circulating liposome modified with c(RGD-ACP-K). The present invention pertains to the field of pharmaceutical preparations, in particular to the field of targeted pharmaceutical preparations. More specifically, the present invention relates to a long-circulating liposome, the surface of the liposome being modified with c(RGD-ACP-K), and the liposome comprising doxorubicin or a pharmaceutically acceptable salt thereof such as doxorubicin hydrochloride as an anti-cancer active agent. The long-circulating liposome can targetedly deliver the anti-cancer active agent into tumor neovascular endothelial cells and tumor cells and can prolong the circulation time of the liposome in vivo, thereby enhancing the therapeutic effect of anti-tumor medicaments.

Long-circulating liposome modified with c(RGD-ACP-K)

Growing community of inventors

Beijing, China

Yue Su