Shanghai Pharmaceuticals Holding Co., Ltd.

Shanghai One Gold Energy-saving Technology Co., Ltd

Ecolab USA Inc.

Yue Ming Zhou

Biao Yu

Jing Lu

Gang Pei

Xin Cao

Shichao Huang

Fuchun Shi

Yuqian An

Jinlie Zhou

Jian Shen

Ling Feng Han

Yin Yin Tong

The present invention relates to a novel therapeutic drug for a neurodegenerative disease and an application thereof. Provided is a novel compound of formula (I). The compound can effectively facilitate the proliferation of neural stem cells in both in vitro and in vivo experiments and can be used as a treatment approach for facilitating neuroregeneration to fight against cognitive decline associated with aging or a neurodegenerative disease.

Therapeutic drug for neurodegenerative disease and application thereof

The present invention relates to a novel compound for preventing or treating neurodegenerative diseases and use thereof. Provided is a novel compound of Formula (I). The compound can effectively promotes the proliferation of neural progenitor cells in both in vitro and in vivo experiments, and can serves as a treatment approach to promote nerve regeneration to fight against cognition impairment associated with aging and neurodegenerative diseases.

Compound for preventing or treating neurodegenerative disease and application thereof

The present invention provides a use of an inorganic salt or acid capable of producing free phosphate or fluoride ion in reducing the hardness and/or alkalinity of a water system containing residual antiscalant. In the lab test, it is found that the addition of a suitable amount of sodium phosphate or sodium fluoride may induce alkalinity reduction as well as hardness reduction. The production efficiency can be enhanced since the scaling was relieved and heat exchange efficiency can be improved. Meanwhile, lower scaling stress also means lower antiscalant dosage and cost, and thus the total operation cost can be reduced.

Use of an inorganic salt or acid in reducing the hardness and/or alkalinity of a water system

An external insulation wall having grid-reinforced insulation board anchored with mechanical devices includes: a base course wall (), wherein a leveling and bonding layer (), grid-reinforced insulation boards (), plastic expansion anchor bolts (), a thin plaster protecting layer (), and a finishing layer () are provided on the base course wall () from inside to outside in turn. Holes are dilled on the grid-reinforced insulation boards (), and the grid-reinforced insulation boards () are directly fixed on the base course wall with the plastic expansion anchor bolts (), in such a manner that all load of an external insulation system is born by the plastic expansion anchor bolts (), and the plastic expansion anchor bolts () transmits the load to the base course wall (). The external insulation wall can solve technical problems of low bearing capacity and difficult surface treatment caused by an old base course wall.

External insulation wall having grid-reinforced insulation board mechanically anchored

An external insulation wall provided with a reinforced polystyrene laminate anchored by a mechanical fixing device is provided. A leveling binder layer () applied on a basic layer wall () is used as a binder layer, and a reinforced polystyrene laminate () is applied before the leveling binder layer () is dried. The reinforced polystyrene laminate () is directly fixed on the basic layer wall () by plastic expansion anchor bolts () through holes drilled on a surface of the reinforced polystyrene laminate (). A standard tension load limit of an external thermal insulation system is increased by the reinforced polystyrene laminate with efficient help of the plastic expansion anchor bolts (). Therefore, the external insulating wall provided with a reinforced polystyrene laminate anchored by a mechanical fixing device is especially suitable for external thermal insulation energy saving engineering on conventional building walls.

External insulated wall provided with reinforced polystyrene laminate anchored by mechanical fixing device

Growing community of inventors

Shanghai, China

Yue Ming Zhou