Southwest Petroleum University

Chengdu Baiyu Pharmaceutical Co., Ltd

Yue Gao

Yi Sun

Hongjun Zhu

Hongzhu Chu

Meiwei Wang

Guizhuan Su

Shuxian Jiang

Jinze Song

Shuai Liu

Lingfeng Xiong

The present invention relates to an amide derivative and use thereof in medicine, and specifically to an amide derivative shown as general formula (I) or a stereoisomer, solvate, metabolite, deuteride, prodrug, pharmaceutically acceptable salt or cocrystal thereof, a pharmaceutical composition containing the same, and use of the compound or the composition disclosed herein in preparing an NLRP3 inhibitor.

Amide derivative and preparation method therefore and use thereof in medicine

The present invention discloses a sand control device for marine hydrate production, which comprises a top motor, a bottom motor, and an inner-layer sand control cylinder, an outer-layer sand control cylinder and an outer-layer sand control screen coaxially arranged from inside to outside, wherein the top motor and bottom motor are configured to control the inner-layer sand control cylinder and the outer-layer sand control cylinder to rotate reversely, and wherein a plurality of sand retaining balls are provided between the inner-layer sand control cylinder and the outer-layer sand control cylinder and between the outer-layer sand control cylinder and the outer-layer sand control screen. According to the present invention, the arrangement of the inner-layer sand control cylinder and the outer-layer sand control cylinder rotating reversely can effectively prevent formation sand from accumulating on the surface of a sand control screen pipe and blocking the sand control screen pipe.

Sand control device for marine hydrate production

Growing community of inventors

Sichuan, China

Yue Gao