Avalanche Technology, Inc.

Headway Technologies, Incorporated

Cisco Technology, Inc.

Other

Applied Cells Inc.

La Pierres, Inc.

Kabushiki Kaisha Toshiba

Tdk Corporation

Dten, Inc.

Magic Technologies, Inc.

Yuchen Zhou

Yiming Huai

Zihui Wang

Kunliang Zhang

Huadong Gan

Kenichi Takano

Joe Smyth

Rajiv Yadav Ranjan

Min Li

Jing Zhang

Roger Klas Malmhall

Moris Musa Dovek

Bing K Yen

Xiaobin Wang

Xuhui Jin

Erhard Theodor Schreck

Ebrahim Abedifard

Xiaojie Hao

Yibin Yang

Tobias Maletzky

Yimin Guo

Kimihiro Satoh

Chia Alex Tsai

Dong Ha Jung

Hieu Tieu

Chao Uei Wahng

Zhigang Bai

Kowang Liu

Ioan Tudosa

Parviz Keshtbod

Lijie Guan

Rajagopalan Janakiraman

Glen A Garfunkel

Grace Lim Gorman

Liejie Guan

Wei Liu

Katsuhiko Koui

Kenichiro Yamada

Tong Zhao

Soichi Oikawa

Joseph Francis Smyth

David Hu

Alex Tsai

Jin Guo

Sally Tung

Mahmood Mozaffari

PoKang Wang

Jinxin Dong

Richard Stewart

Weng Hong Chan

Hitoshi Iwasaki

Ru-Ying Tong

Cheng Tzong Horng

Masayuki Takagishi

Mehdi Asnaashari

Yan Wu

Akihiko Takeo

Tomomi Funayama

Wenyu Chen

Liqin Dong

Masahiro Takashita

Benjamin P Chen

Min Zheng

Chiajen Tsai

Dayu Zhou

Patnala Debashis Rao

Yuefeng Jiang

Fang Yang

Minjie Lin

Jeffrey Cai

Xiaopu Zhang

Yu-Hsai Chen

Fengxiang Pang

Jinlong Fan

Pengfa Xu

Xinglong Wang

Zhi Gang Bai

Bernardo Sardinha

Kunliag Zhang

A microfluidic device for sorting biological objects includes a microfluidic chip including a planar substrate having first and second planar surfaces, the planar substrate including first and second networks of channels recessed respectively from the first and second planar surfaces and fluidically connected by way of at least a through-hole in the planar substrate; a first lid attached to the first planar surface of the planar substrate and substantially covering the first network of channels; and a second lid attached to the second planar surface of the planar substrate and substantially covering the second network of channels; and one or more piezoelectric transducers attached to the first lid and/or the second lid and configured to generate first and second acoustic standing waves in a first linear channel of the first network of channels and a second linear channel of the second network of channels, respectively.

Microfluidic chip for acoustic separation of biological objects

A system for aseptically transferring a liquid substance comprises a sterilized vial filled with the liquid substance and sealed with a sterilized septum; a sterilized fluidic assembly including a piercing member including therein first and second channels and having a tip end that operably punctures the sterilized septum, the first and second channels having first and second channel openings at the tip end; a manual air pump; an inlet line fluidically connects the manual air pump to the first channel of the piercing member; and an outlet line fluidically connected to the second channel of the piercing member at one end and hermetically sealed at the other end; and a sterilized pouch enclosing and hermetically sealing the sterilized vial and the piercing member and operably allowing the piercing member to puncture the sterilized septum when the piercing member is manually pushed from the exterior of the sterilized pouch.

System and method for aseptically transferring fluid

The current invention relates to the method and apparatus to separate biological entities from a fluid sample. The claimed methods separate biological entities based on size of entities by using acoustic pressure nodes in a microfluidic device. The claimed methods further separate biological entities with magnetic labels and by using a magnetic device. The claimed methods further include combination of microfluidic devices and magnetic devices to separate biological entities from a fluid sample.

Methods and apparatus to separate biological entities

A microfluidic system for separating biological entities includes a cooling device including a thermoelectric heat pump, a first fan, and a first heat exchanger disposed between the first fan and the thermoelectric heat pump; a first housing structure having a first shell that encases the first fan and the first heat exchanger; a microfluidic device and one or more piezoelectric transducers attached thereto; and a second housing structure reversibly attached to the first housing structure and having a second shell that encloses therein the microfluidic device and the one or more piezoelectric transducers. When the first and second housing structures are coupled, a first air passage is formed between a side of the first heat exchanger and an end of the microfluidic device, a second air passage is formed between the first fan and the piezoelectric transducers, thereby allowing air to circulate between the first and second air passages.

Microfluidic system including cooling device

The current invention relates to the device and method to separate biological entities from a sample fluid by a microfluidic device. The claimed methods separate biological entities by differentiating the sizes of the biological entities with ultrasound modes. The claimed methods further utilize a multi-staged design that removes smaller size entities at earlier and wider sections and concentrates larger entities at later and narrower sections of a microfluidic channel.

Microfluidic device and method of use

A spin-transfer torque magnetic random access memory (STTMRAM) element employed to store a state based on the magnetic orientation of a free layer, the STTMRAM element is made of a first perpendicular free layer (PFL) including a first perpendicular enhancement layer (PEL). The first PFL is formed on top of a seed layer. The STTMRAM element further includes a barrier layer formed on top of the first PFL and a second perpendicular reference layer (PRL) that has a second PEL. The second PRL is formed on top of the barrier layer. The STTMRAM element further includes a capping layer that is formed on top of the second PRL.

Memory system having thermally stable perpendicular magneto tunnel junction (MTJ) and a method of manufacturing same

The current invention generally relates to apparatus and method to analyze and separate biological entities, including cells, bacteria and molecules from human blood, body tissue, body fluid and other human related biological samples. The claimed apparatus and method analyze, or detect, biological entities based on optical signals received from said entities by using optical detectors. The claimed apparatus and method further separate biological entities with using micro-actuator activated sorting devices.

Biological entity separation device and method of use

The current invention relates to the method and apparatus to magnetically separate biological entities with magnetic labels from a fluid sample. The claimed magnetic separation device removes biological entities with magnetic labels from its fluidic solution by using a soft-magnetic center pole with two soft-magnetic side poles. The claimed device further includes processes to dissociate entities conglomerate after magnetic separation.

Magnetic separation device and method of use

A system automatically frames locations by detecting a user's presence within a virtual detection space. The system detects sound in the detection space and converts the sound into electrical signals. The electrical signals are converted into a digital signals at common or periodic sampling rates. The system identifies speech segments in the digital signals and attenuates noise like components within or adjacent to them. The system identifies the physical locations of a speech source generating the speech segments and automatically adjusts a camera framing based on the estimated location of the active speech source generating the speech segments.

Auto-framing through speech and video localizations

A system automatically controls an electronic device's audio by detecting an active sound source presence within an auditory detection space. The system transitions the electronic device to selectively output a desired sound when the active sound source presence is detected and detects sound in the auditory detection space. The system enhances sound and transforms it into electrical signals. The system converts the electrical signals into a digital signal and identifies active sound segments in the digital signals. The system attenuates noise components in the digital signals and locates the physical location of the active sound source. It adjusts an output automatically by muting a second sound source in a second detection space.

Active sound control

The invention describes a family of sensors for assaying macro-molecules and/or biological cells in solution. The invention also describes methods of making and using the sensors. Each sensor has the form of a well (a hollow cylinder having a floor but no lid) or a trench whose walls comprise a plurality of GMR or TMR devices. Suitably shaped magnets located below each well's floor pull labeled particles into the well/trench and up against the inner wall where a field gradient orients them for optimum detection. Any unattached labels that happen to also be in the well/trench are removed through suitably sized holes in the floor.

Discrete contact MR bio-sensor with magnetic label field alignment

The current invention relates to the methods to achieve virtual reality with making virtual objects not under focus of a viewer in virtual scenes appear defocused, and making objects under focus of said viewer appearing focused and clear to said viewer. The current invention also relates to the methods to achieve augmented reality with making virtual objects in virtual scenes associated with real objects not under focus of a viewer in real scenes appear defocused to said viewer in said virtual scene, and making virtual objects in virtual scenes associated with real objects being under focus of a viewer in real scenes appear focused to said viewer in said virtual scene.

Method of utilizing defocus in virtual reality and augmented reality

The present invention is directed to a magnetic memory element including a magnetic free layer structure having a variable magnetization direction perpendicular to a layer plane thereof; a non-magnetic metal layer formed adjacent to the magnetic free layer structure; an oxide layer formed adjacent to the non-magnetic metal layer; an insulating tunnel junction layer formed adjacent to the magnetic free layer structure opposite the non-magnetic metal layer; a first magnetic reference layer formed adjacent to the insulating tunnel junction layer; a second magnetic reference layer separated from the first magnetic reference layer by a perpendicular enhancement layer; an antiferromagnetic coupling layer formed adjacent to the second magnetic reference layer; and a magnetic fixed layer structure formed adjacent to the antiferromagnetic coupling layer. The first and second magnetic reference layers have a first invariable magnetization direction substantially perpendicular to layer planes thereof. The magnetic fixed layer structure has a second invariable magnetization direction substantially opposite to the first invariable magnetization direction.

Magnetic random access memory with perpendicular enhancement layer

An STTMRAM element includes a magnetic tunnel junction (MTJ) having a perpendicular magnetic orientation. The MTJ includes a barrier layer, a free layer formed on top of the barrier layer and having a magnetic orientation that is perpendicular and switchable relative to the magnetic orientation of the fixed layer. The magnetic orientation of the free layer switches when electrical current flows through the STTMRAM element. A switching-enhancing layer (SEL), separated from the free layer by a spacer layer, is formed on top of the free layer and has an in-plane magnetic orientation and generates magneto-static fields onto the free layer, causing the magnetic moments of the outer edges of the free layer to tilt with an in-plane component while minimally disturbing the magnetic moment at the center of the free layer to ease the switching of the free layer and to reduce the threshold voltage/current.

Perpendicular magnetic tunnel junction (pMTJ) with in-plane magneto-static switching-enhancing layer

The current invention relates to the method and apparatus to magnetically separate biological entities with magnetic labels from a fluid sample. The claimed methods separate biological entities with magnetic labels by using a magnetic device. The claimed methods further include processes to dissociate biological entities magnetic conglomerate after magnetic separation.

Magnetic biological entity separation device and method of use

Growing community of inventors

San Jose, CA, United States of America

Yuchen Zhou