Baxter International Inc.

Yuan-pang Samuel Ding

Michael T K Ling

Lecon Woo

Chuan Qin

Sherwin S Shang

Tahua Yang

Patrick T Ryan

Craig Sanford

Ketan N Shah

Sarah Louise Corbin

George Dillon

Dale Pennington

Robert Wojnarowski

Richard Mennenoh

Ying-Cheng Lo

Patrick R Balteau

Larry A Rosenbaum

Birendra K Lal

Gregg Nebgen

Stanley Westphal

Michael W Scharf

Donna L Rostron

Susan R Mizener

Lillian G Zakarija

Varsha Kalyankar

Keith M K Anderson

Michael K Oberhaus

Tao Chang

Leoon Woo

Daniel Beedon

Biran Lal

Colleen S Cramer

Birenda K Lal

H&eacute;naut J Eric

The present invention provides a flowable materials container. The container has a first sidewall and a second sidewall sealed together along a peripheral seam to define a fluid chamber. At least one sidewall is a film having at least one layer of blend of a first component selected from the group of: (1) ethylene and &#x3b1;-olefin copolymers having a density of less than about 0.915 g/cc, (2) ethylene copolymerized with lower alkyl acrylates, (3) ethylene copolymerized with lower alkyl substituted alkyl acrylates and (4) ionomers, the first component being present in an amount from about 99% to about 55% by weight of the blend, a second component in an amount by weight of the blend from about 45% to about 1% and consists of one or more polymers of the group: (1) propylene containing polymers, (2) polybutene polymers, (3) polymethylpentene polymers, (4) cyclic olefin containing polymers and (5) bridged polycyclic hydrocarbon containing polymers; and the film has a modulus of elasticity when measured in accordance with ASTM D882 of less than about 60,000 psi, an internal haze when measured in accordance with ASTM D1003 of less than about 25%, an internal adhesion ranking of greater than about 2, a sample creep at 120&#xb0; C. under 27 psi loading of less than or equal to 150% for a film having a thickness of from about 5 mils to about 15 mils, and the film can be heat sealed into a container having seals wherein the seals remain intact when the container is autoclaved at 121&#xb0; C. for one hour.

Containers and peelable seal containers of new non-PVC material

A polymer blend for fabricating medical products having a first 1,2 polybutadiene present from about 1% to about 99% by weight of the blend and having a first melting point temperature; and a second 1,2 polybutadiene present from about 1% to about 99% by weight of the blend and having a second melting point temperature higher than the first melting point temperature.

Method and process for enhancing properties and medical tubing performance in a polybutadiene material

The present invention provides a polymer blend for fabricating monolayer films or a layer within a multilayer film. The blend has a first component and a second component. The first component is selected from the group of: (1) an ethylene and &#x3b1;-olefin copolymer having a density of less than about 0.915 g/cc, (2) lower alkyl acrylates, (3) lower alkyl substituted alkyl acrylates and (4) ionomers. The first component should be present in an amount from about 99% to about 55% by weight of the blend. The second component in an amount by weight of the blend from 45% to about 1% and consists of one or more polymers of the group: (1) propylene containing polymers, (2) polybutene polymers, (3) polymethylpentene polymers, (4) cyclic olefin containing polymers and (5) bridged polycyclic hydrocarbon containing polymers. When the blend is fabricated into a film it has a modulus of elasticity when measured in accordance with ASTM D882 of less than about 60,000 psi, an internal haze when measured in accordance with ASTM D1003 of less than about 25%, an internal adhesion ranking of greater than about two, a sample creep at 120&#xb0; C. under 27 psi loading of less than or equal to 150% for a film having a thickness from about 5 mils to about 15 mils, and the film being capable or being heat sealed into a container having seals wherein the seals remain intact when the container is autoclaved at 121&#xb0; C. for one hour.

Autoclavable, non-adherent, heat sealable polymer blends for fabricating monolayer and multiple layered films

The present invention provides a multilayer film. The film has a first layer of a blend of a first component selected from the group of: (1) ethylene and a-olefin copolymers having a density of less than about 0.915 g/cc, (2) ethylene copolymerized with lower alkyl acrylates, (3) ethylene copolymerized with lower alkyl substituted alkyl acrylates and (4) ionomers, the first component being present in an amount from about 99% to about 55% by weight of the blend, a second component in an amount by weight of the blend from about 45% to about 1% and consists of one or more polymers of the group: (1) propylene containing polymers, (2) polybutene polymers, (3) polymethylpentene polymers, (4) cyclic olefin containing polymers and (5) bridged polycyclic hydrocarbon containing polymers; a second layer attached to the first layer; and the film has a modulus of elasticity when measured in accordance with ASTM D882 of less than about 60,000 psi, an internal haze when measured in accordance with ASTM D1003 of less than about 25%, an internal adhesion ranking of greater than about 2, a sample creep at 120&deg; C. under 27 psi loading of less than or equal to 150% for a film having a thickness of from about 5 mils to about 15 mils, and the film can be heat sealed into a container having seals wherein the seals remain intact when the container is autoclaved at 121 &deg; C. for one hour.

Multiple layer film of a new non-PVC material

The present invention provides a method for assembling a medical device using solvent bonding techniques. The method includes the steps of: (1) providing a first article of a polymer composition having (a) a first component of a homopolymer or copolymer obtained using monomers of cyclic olefin or a bridged polycyclic hydrocarbon, the first component being present in an amount from about 30% to about 100% by weight of the composition and (b) a second component from 0-70% by weight of the composition; (2) providing a second article of a material selected from the group of low crystallinity polymers; (3) applying a solvent to one of the first article or the second article to define an interface area; and (4) bonding the first article to the second article along the interface area.

Method for solvent bonding polyolefins

The present invention provides a method for using a polymeric cement to assemble medical devices. The method includes the steps of: (1) providing a first article of a low crystallinity polymer; (2) providing a second article of a low crystallinity polymer; (3) providing a cement composition having a first component of a cyclic olefin containing polymer or a bridged polycyclic hydrocarbon containing polymer and a second component of an effective amount of a solvent having a solubility parameter of less than about 20 (MPa) ; applying the cement composition to one of the first and second articles to define a bonding area; and (4) attaching the first article to the second article along the bonding area to fixedly attach the first article to the second article.

Solvent bonding method for polyolefin materials

The present invention provides a polymer composition having: a first component selected from homopolymers and copolymers of cyclic olefin containing polymers and bridged polycyclic hydrocarbon containing polymers, the first component being present in an amount from about 1-99% by weight of the composition; and a second component is selected from homopolymers and copolymers of a diene having from 4 to 12 carbons, the second component being present in an amount from about 99% to about 1% by weight of the composition.

Cycloolefin blends and method for solvent bonding polyolefins

The present invention provides a multiple layer thermoplastic structure of a (1) skin layer selected from the group consisting of polypropylene, ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc, and ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc blended with an ethylene and a-olefin copolymers having a density less than about 0.930 g/cc, the skin layer having a thickness of greater than about 3.0 mils; (2) a radio frequency susceptible layer adhered to the skin layer, the radio frequency susceptible layer having a dielectric loss greater than 0.05 at 1-60 MHz and at temperatures of ambient to 250&deg; C., the radio frequency susceptible layer having: (a) a first polyolefin selected from the group consisting of polypropylene and polypropylene copolymers, (b) a second polyolefin selected from the group consisting of ethylene copolymers, ultra-low density polyethylene, polybutene, and butene ethylene copolymers; (c) a radio frequency susceptible polymer selected from the group consisting of (i) ethylene copolymers having 50-85% ethylene content with comonomers selected from a first group consisting of acrylic acid, methacrylic acid, ester derivatives of acrylic acid with alcohols having 1-10 carbons, ester derivatives of methacrylic acid with alcohols having 1-10 carbons, vinyl acetate, and vinyl alcohol (ii) homopolymers and copolymers containing at least one segment of urethanes, esters, ureas, imides, sulfones, and amides, and (d) a compatibilizing agent of a styrene and hydrocarbon copolymer; wherein the structure when fabricated into a 50 ml container has a water vapor transmission rate of less than 8% by weight after the container has been autoclaved at 121&deg; C. for 20 minutes and stored for 90 days in an environmentally regulated compartment having 15% relative humidity at 40&deg; C.

Multi-layered polymer based moisture barrier structure for medical grade products

A steam sterilizable monolayer medical tubing comprising a blend of a melt strength enhancing agent of a homopolymer or copolymer of polypropylene having free-end long chain branches of propylene units, a melt flow index of greater than 10 and in an amount of 1-10% by weight and a second component selected from the group of (i) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene and (ii) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene to which has been grafted, an alpha, beta-olenfically unsaturated monocarboxylic or dicarboxylic acid reagent.

Low modulus and autoclavable monolayer medical tubing

The present invention provides a medical device of a polymer composition. The composition has a first component obtained by copolymerizing a norbornene monomer and an ethylene monomer, the first component being in an amount from about 1-99% by weight of the composition; and a second component of an ethylene and &agr;-olefin copolymer, the &agr;-olefin having 6 carbons, the second component being in an amount from about 99% to about 1% by weight of the composition.

The present invention provides a polymer composition having a first component obtained by copolymerizing a norbornene monomer and an ethylene monomer, the first component being in an amount from about 1-99% by weight of the composition; and a second component of an ethylene and &agr;-olefin copolymer, the &agr;-olefin having 6 carbons, the second component being in an amount from about 99% to about 1% by weight of the composition.

The present invention provides a method of using a medical tubing with a pump for administering measured amounts of a beneficial fluid over time to a patient comprising the steps of providing a tubing having a first layer selected from the group consisting of ethylene homopolymers and ethylene copolymers, wherein the copolymers of ethylene are an ethylene monomer copolymerized with at least one monomer selected from the group consisting of lower alkyl olefins, lower alkyl esters of a carboxylic acid, and lower alkene esters of a carboxylic acid, the lower alkyl and lower alkene having from 3 to 18 carbons, the tubing having been exposed to a sterilization dosage of radiation of from about 15 to about 45 kGys; and pumping fluid through the tubing with the pump.

Growing community of inventors

Vernon Hills, IL, United States of America

Yuan-pang Samuel Ding