Massachusetts Institute of Technology

National Taiwan University

The University of Arizona

Yonglin Healthcare Foundation

Yuan Luo

George Barbastathis

Se Baek Oh

Jennifer K Barton

Raymond K Kostuk

Yu-Hsuan Chuang

Yu-Zi Lin

Pan-Chyr Yang

Din Ping Tsai

A system for quantitative differential phase contrast microscopy with isotropic transfer function utilizes a modulation mechanism to create a detection light field having a radial or other axial orientation of optical intensity gradient or other distribution. A condenser generates an off-axis light field to project onto an object under examination, thereby generating an object light field, which is then guided to an image capturing device through an objective lens for capturing images. A differential phase contrast algorithm is applied to the images for obtaining a phase, thereby a depth information corresponding to the phase can be obtained to reconstruct the surface profile of the object.

System for quantitative differential phase contrast microscopy with isotropic transfer function

The present invention provides a device for generating an abrupt autofocusing beam, comprising a light source module, a metasurface phase modulating element, and a focus lens, wherein the light source module generates an incident light beam, the metasurface modulating element has a first optical receiving surface for receiving the incident light beam, and an optical emitting surface having a plurality of dielectric nano-structures formed thereon for modulating the incident light beam into a diffracted light beam wherein the plurality of nano-structures respectively corresponding to optical-phase mask patterns, and the focus lens is arranged at a side of the optical receiving surface for performing optical Fourier transform of the diffracted light beam obtained from the metasurface phase modulating element.

Metasurface based device for generating abrupt autofocusing beam

A volume holographic imaging system, apparatus, and/or method enables the projection of a two-dimensional (2D) slice of a four-dimensional (4D) probing object. A 4D probing source object is illuminated to emit or scatter an optical field. A holographic element having one or more recorded holograms receives and diffracts the optical field into a diffracted plane beam having spectral information. A 4-f telecentric relay system includes a pupil filter on the relayed conjugate plane of the volume hologram and images the pupil of the volume hologram onto the front focal plane of the collector lens. A collector lens focuses the diffracted plane beam to a 2D slice of the 4D probing source object. The focused 2D slice is projected onto a 2D imaging plane. The holographic element may have multiple multiplexed holograms that are arranged to diffract light from the corresponding slice of the 4D probing source object.

System, method and apparatus for phase contrast enhanced multiplexing of images

System, method and apparatus for wavelength-coded multi-focal microscopy

A volume holographic imaging system, apparatus and/or method enables the projection of a two-dimensional (2D) slice of a four-dimensional (4D) probing object A 4D probing source object is illuminated to emit or scatter an optical field. A holographic element having one or more recorded holograms receives and diffracts the optical field into a diffracted plane beam having spectral information. A 4-ftelecentric relay system includes a pupil filter on the relayed conjugate plane of the volume hologram and images the pupil of the volume hologram onto the front focal plane of the collector lens. A collector lens focuses the diffracted plane beam to a 2D slice of the 4D probing source object. The focused 2D slice is projected onto a 2D imaging plane. The holographic element may have multiple multiplexed holograms that are arranged to diffract light from the corresponding slice of the 4D probing source object.

System, method and apparatus for contrast enhanced multiplexing of images

A volume holographic imaging system enables the projection of a two-dimensional (2D) slice of a four-dimensional (4D) object. The 4D source object is illuminated to emit or scatter an optical field. A holographic element having one or more recorded holograms receives and diffracts the optical field into a diffracted plane beam. A phase mask is encoded in one or more multiplexed holographic gratings of the holographic element using a spatial filter. A collector lens focuses the diffracted plane beam to a 2D slice of the 4D probing source object. The focused 2D slice is projected onto a 2D imaging plane. The holographic element may have multiple multiplexed holograms that are arranged to diffract light from a corresponding slice of the 4D probing source object to a non-overlapping region of the detector.

Growing community of inventors

Taipei, Taiwan

Yuan Luo