Molecular Probes, Inc.

Yu Zhong Zhang

Richard P Haugland

Hee Chol Kang

Michael A Kuhn

K Sam Wells

John Michael Brinkley

The invention is a novel fluorescently labeled microparticle, where the microparticle internally incorporates at least one dipyrrometheneboron difluoride dye. Appropriate selection of substituents results in dipyrrometheneboron difluoride derivatives that, when incorporated into polymer microparticles, give the desired excitation and emission wavelengths. The spectral characteristics of the labeling dyes in liquid are not greatly changed when the dye is incorporated into the particles, and the spectral excitation and emission wavelengths are compatible with commonly used filter sets. Other embodiments of the fluorescent microparticles include additional dyes and/or bioreactive substances.

Growing community of inventors

Eugene, OR, United States of America

Yu Zhong Zhang