Boehringer Ingelheim International Gmbh

Boehringer Ingelheim Pharma Gmbh & Co Kg

Yu Yang

Roger John Snow

Jiang-Ping Wu

Alexander Heim-Riether

Daniel R Goldberg

Derek Cogan

Alan David Swinamer

Zhaoming Xiong

Donghong Amy Gao

Lana Louise Smith Keenan

Ingo Andreas Mugge

Craig Andrew Miller

Wang Mao

Philip Dean Ramsden

Kaka Dey

John Edward Mangette

Disclosed is a compound of formula (I). Wherein R, RAr and Cy are as defined herein, or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions of the compound of formula (I), methods of making the compounds of formula I, and methods of using the compounds of formula (I) to treat a disorder associated with activation of CCR10. 

[object Object]

The invention relates to a compound of formula (I): or a tautomer thereof or a pharmaceutically acceptable salt thereof, wherein Rto R, W, X, Y, Z, and n are as defined herein. The invention also relates to methods of using the compounds of formula (I) and compositions thereof to treat various diseases and disorders in a patient. The invention also relates to processes for preparing the compounds of formula (I) and intermediates useful in these processes.

CCR10 antagonists

Growing community of inventors

Clark, NJ, United States of America

Yu Yang