Glaxo Group Limited

Glaxosmithkline Intellectual Property Development Limited

Yu Xue

Ian Kirby

Alexander Harrison Taylor

Thomas Matthew Webb

Zdenka Ludmila Jonak

Kyung Oh Johanson

Stephen H Trulli

John Richard White

Judithann M Lee

Neil James Clarke

Zdenka Haskova

Alex H Taylor

Christopher B Hopson

Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis.

CD127 binding proteins

The present disclosure relates to antigen binding proteins, such as antibodies, that bind to HER3, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present disclosure also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with breast cancer, ovarian cancer, prostate cancer, bladder cancer, pancreatic, gastric, melanoma and other cancers that overexpress HER3.

Antigen binding proteins

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King of Prussia, PA, United States of America

Yu Xue