Chongqing Lummy Pharmaceutical Co., Ltd.

Sichuan Yingrui Pharmaceutical Technology Company

Yu Qiu

Yun Zhang

Yuan Yuan

Ke Li

Hongyu Li

Bing Zhou

Xiaohai Tang

Yuanfang Huang

Pingfang Xia

Yeli Huang

Liuying Zhao

Lilin Peng

Xin Song

The present invention provides a nanocarbon-iron composite system which is a composite structure formed by interaction of acid-treated nanocarbon serving as a carrier, with and ferrous ions and/or ferric ions in an iron salt. In an in-vitro experiment and an animal experiment, the nanocarbon-iron composite system of the present invention shows a very efficient inhibition effect on solid tumors containing liver cancer, breast cancer and cervical cancer and has an excellent targeting property. Accordingly, the present invention further provides a preparation method of the nanocarbon-iron composite system, use of the nanocarbon-iron composite system in preparation of a drug for treating solid tumors, and a suspension for injection based on the nanocarbon-iron composite system.

Nanocarbon-iron composite system as well as composition, preparation method and use thereof

A preassembled medicine mixer comprises a rotary sleeve (), a guide sleeve I (), a guide sleeve II (), a guide part, a dosing barrel (), and a dosing double needle (). The guide sleeve I () extends into the guide sleeve II () and is connected to the rotary sleeve (). A guide groove () is provided on the side wall of the guide sleeve I (), and two ends of the guide groove () are extended by a distance towards opposite directions. A guide spiral groove () is provided on an inner wall of the guide sleeve II (). The guide part is disposed in the guide sleeve I () and has a guide block () at the outer side thereof. The guide block () penetrates through the guide groove () and extends into the guide spiral groove (). In use, the rotary sleeve () is rotated to drive the guide part to rapidly move downwards and push a medicine container (); an upper needle tip of the dosing double needle () pierces a sealing plug on the medicine container (), and a lower needle tip pierces a diaphragm () in an interface (), so that the medicine container () is instantly communicated with an infusion container (), thereby implementing sterile closeness during the entire process of transportation, storage, butt joint, medicine mixing, and infusion.

Preassembled medicine mixer

An integrated medicine mixing interface comprising a medicine mixing mouth (), hard double interfaces () and a medicine feed needle (). The hard double interfaces () comprise a base (), a medicine mixing interface () and an infusion interface (). The medicine mixing mouth () and the medicine mixing interface () are integrated. When using the integrated medicine mixing interface, it is only necessary to weld the base () to the bag body of a soft infusion bag () and integrate the medicine mixing mouth () with the medicine mixing interface on the hard double interfaces () without adopting a hose connection and an easily folding handle, which not only reduces hose installation location, but also avoids welding leakage brought about by hose welding defects. Moreover, the structure is simple and the costs are low.

Integrated medicine mixing interface

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Chongqing, China

Yu Qiu