Tci Co., Ltd.

Yu-Ling Wang

Yung-Hsiang Lin

The present disclosure provides peptides comprising a motif having four amino acids, wherein each of the amino acids at N-terminus and C-terminus of the sequence independently has a same or different positively charged side chain, and each of the amino acids between the N-terminal and C-terminal of the motif independently has a same or different uncharged side chain. The present disclosure surprisingly found that these peptides have advantageous effects in inhibiting or decreasing collagen breakdown, increasing production of collagen, elastin and/or hyaluronic acid, retarding aging, improving skin and inhibiting inflammation.

Biomimetic peptides derived from biological source and their uses in retarding aging and improving skin

A method for preventing aging of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 6. Each of the amino acid sequence is a peptide of fish skin. The composition has anti-aging and cellular health maintaining capabilities. In addition, the composition can also be used for increasing collagen content, improving skin collagen density, improving skin moisture, minimizing skin pores, reducing wrinkles or achieving a combination of these effects.

Method for preventing aging with bioactive compound

A method for improving a skin condition of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 11. Each of the amino acid sequence is a peptide of fish skin.

Method for improving skin condition with bioactive compound

A method for treating eye inflammation by using an anti-inflammatory composition is provided. The bioactive compound in the anti-inflammatory composition is a peptide having an amino acid sequence as set forth in SEQ ID NO.: 1. The amino acid sequence is a peptide fragment derived from cowhide. The composition may be administered to the eye of a human subject for reducing the expression of vascular endothelial growth factor A (VEGFA) gene, interleukin-1 beta (IL-1&#x3b2;) gene, and/or interleukin-8 (IL-8) gene.

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Taipei, Taiwan

Yu-Ling Wang