Industrial Technology Research Institute

Yu-Fang Yen

Wen-Pin Hsieh

Chu-Hsuan Chen

Fen-Fei Lin

Yi-Ting Tung

Chien-An Chen

Cheng-Tai Chen

Hui-Ju Shen

Yi-Yen Yuan

Yi-Yun Yuan

An extracellular vesicle separation method, a colloidal particle, and a preparation method thereof are provided. The colloidal particle is used for extracellular vesicle separation, and includes 2 wt % to 6 wt % of agarose. The colloidal particle has a particle size of 25 μm to 500 μm, and is surface-modified with biocompatible molecules. The biocompatible molecules include sodium carboxymethyl cellulose (CMC), methyl cellulose (MC), glycine, aspartic acid, glutamic acid, bovine serum albumin (BSA), fetal bovine serum (FBS), or a combination thereof.

Extracellular vesicle separation method, colloidal particle and preparation method thereof

A method of measuring hematocrit is provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a plurality of sets of square wave voltages are intermittently applied to the pair of electrodes based on a square wave voltammetry method to obtain a plurality of feedbacks related to hematocrit. An interval between two adjacent sets of square wave voltages ranges from 0.1 seconds to 4 seconds. A feedback of an n-th set of square wave voltages is obtained to calculate a hematocrit value of the whole blood sample and n is a positive integer greater than 1. A hematocrit value is calculated according to the feedback.

Method of measuring hematocrit and method of testing blood

The present disclosure provides a method for detecting an analyte concentration. The method includes providing a test strip, which includes a first electrode set including a first reaction area, a second electrode set including a second reaction area, and a reaction reagent layer disposed on the second reaction area. The method includes providing a blood sample and bringing the blood sample into contact with the first electrode set and the second electrode set, applying a first voltage to the first electrode set by voltammetry to obtain a first response value, calculating a hematocrit value according to the first response value, applying a second voltage to the second electrode set to obtain a second response value, and calculating the actual value of the analyte concentration by using the hematocrit value and the second response value.

Methods for measuring analyte concentration

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Yu-Fang Yen