Taiwan Green Point Enterprises Co., Ltd.

China Medical University Hospital

Shine-On Biomedical Co., Ltd.

Yu-Chuan Lin

Der-Yang Cho

Shao-Chih Chiu

Shi-Wei Huang

Chih-Ming Pan

Mei-Chih Chen

Yeh Chen

Pen-Yi Liao

Hui-Ching Chuang

Ai-Ling Lin

Chih-Hao Chen

Sung-Yi Yang

Yi-Cheng Lin

Yi-Wen Chen

Kai-Wen Kan

Ming-You Shie

The present disclosure provides a fusion protein and the nucleic acid encoding sequence thereof, and uses of the same. The fusion protein of the present disclosure achieves the effect of treating cancer, immunoregulation and activating immune cells through various efficacy experiments.

Fusion protein and nucleic acid encoding sequence thereof, and uses of the same

The present disclosure provides an anti-tumor antigen nanobody that specifically binds to a human leukocyte antigen-G. The present disclosure also provides the nucleic acid sequence of the anti-tumor antigen nanobody, use of the anti-tumor antigen nanobody for treating cancer and immune-related disorders, and a method for detecting expression levels of HLA-G.

Anti-tumor antigen nanobody and nucleic acid encoding sequence thereof, and uses of the same

The present disclosure provides an anti-T-cell nanobody that specifically binds to CD3 &#x3b5;. The present disclosure also provides the nucleic acid sequence of the anti-T-cell nanobody, use of the anti-T-cell nanobody for treating cancer, immunoregulation and activating immune cells, and a method for detecting expression levels of CD3 &#x3b5;.

Anti-T-cell nanobody and nucleic acid encoding sequence thereof, and uses of the same

The present disclosure provides an immunomodulation and anti-tumor-related nanobody that specifically binds to a human leukocyte antigen-G, a programmed cell death ligand 1, and CD3 &#x3b5;. The present disclosure also provides the nucleic acid sequence of the immunomodulation and anti-tumor-related nanobody, and use of the immunomodulation and anti-tumor-related nanobody for treating cancer and immune-related disorders.

Immunomodulation and anti-tumor-related nanobody and nucleic acid encoding sequence thereof, and uses of the same

The present disclosure provides an anti-immune-checkpoint nanobody that specifically binds to a programmed cell death ligand 1. The present disclosure also provides the nucleic acid sequence of the anti-immune-checkpoint nanobody, use of the anti-immune-checkpoint nanobody for treating cancer and immune-related disorders, and a method for detecting expression levels of PD-L1.

Anti-immune-checkpoint nanobody and nucleic acid encoding sequence thereof, and uses of the same

An electrochemical biosensor includes a substrate, a plurality of layered active metal parts, a plurality of layered electrodes, a reaction confinement layer, an electrochemical reactive layer and a cover piece. The substrate is formed with through holes each of which is defined by an interior wall surface and penetrates top and bottom surfaces. Each of the layered active metal parts is formed at least upon a respective one of the interior wall surfaces. The layered electrodes are formed on the layered active metal parts. The reaction confinement layer confines a reactor space over a region where the through holes are formed. The electrochemical reactive layer is disposed in the reactor space and is electrically coupled to the layered electrodes.

Electrochemical biosensor and method for producing the same

An illumination assembly includes a substrate, a wiring structure, a reflecting layer and a plurality of light-emitting diodes. The wiring structure is formed on a part of the substrate, and includes a catalyst layer covering the part of the substrate, and a conducting layer formed on the catalyst layer. The reflecting layer is formed on another part of the substrate that is exposed from the wiring structure. The light-emitting diodes are disposed on the wiring structure and are electrically connected to the wiring structure.

Growing community of inventors

Taichung, Taiwan

Yu-Chuan Lin