Bioalliance C.v.

Abgenomics International Inc.

Acer Inc.

Yu-Chi Hsieh

Shih-Yao Lin

Rong-Hwa Lin

Chiu-Chen Huang

Yu-Ying Tsai

Shu-Hua Lee

Feng-Lin Chiang

Li-An Hu

A touch display apparatus and an operating method of the touch display apparatus are provided. An application icon is converted into a corresponding startup gesture icon if a touch operation conforms to an icon conversion operation. Here, the startup gesture icon indicates a gesture operation required for starting up an application corresponding to the startup gesture icon.

Touch display apparatus and operating method thereof

The present disclosure provides anti-folate receptor alpha (FRA) antibody-drug conjugates comprising a hydrophilic self-immolative linker. The present disclosures further provide compositions and methods for treating cancers.

Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof

The present disclosure provides compounds with a hydrophilic self-immolative linker, which is cleavable under appropriate conditions and incorporates a hydrophilic group to provide better solubility of the compound. The compounds of the present disclosure comprise a drug moiety, a targeting moiety capable of targeting a selected cell population, and a linker which contains an acyl unit, an optional spacer unit for providing distance between the drug moiety and the targeting moiety, a peptide linker which can be cleavable under appropriate conditions, a hydrophilic self-immolative linker, and an optional second self-immolative spacer or cyclization self-elimination linker.

Hydrophilic self-immolative linkers and conjugates thereof

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Taipei, Taiwan

Yu-Chi Hsieh