Credo Diagnostics Biomedical Pte. Ltd.

Yu-Cheng Ou

Ying-Ta Lai

Han-Yi Chen

Jim-Yi Liao

Cheng-Yueh Chung

Fan-Yun Huang

Yi-Hsi Chen

Chun-Te Wu

Yu-Wen Huang

Ming-Lung Hung

Shu-Hong Huang

Wei-Hao Liu

Ruei-Yi Tsai

Li-Yu Hsiung

The present invention provides a sample tube for polymerase chain reaction. The sample tube includes a sample tube body having an annular side wall and a bottom wall connected to annular side wall, wherein the annular side wall and the bottom wall form an accommodating space for accommodating a reaction mixture; and a first extension member extending from the bottom wall to the accommodating space, wherein, to carry out PCR, the reaction mixture immerses the first extension member, such that the light from the light source enters into the reaction mixture via the bottom and the bottom wall of the sample tube and the first extension member sequentially.

Sample tube for polymerase chain reaction and polymerase chain reaction device thereof

An analysis cartridge includes a first cover, a second cover, a plurality of containers, a plurality of fluid tunnels and a rotary valve. The second cover has two opposite surfaces, a plurality of first through holes and a second through hole individually penetrate through the two opposite surfaces, and the first cover is attached to the second cover. The plurality of containers are disposed between the first cover and the second cover, with each of the containers being aligned to and filled in the first through holes. The plurality of the fluid tunnels are disposed on the first cover, and each of which is individually connected with a first pipette. The rotary valve is rotatably disposed between the first cover and the second cover to correspond to the second through hole, and a flow channel disposed on the rotary valve is connected with the containers individually.

Analysis cartridge

The present invention discloses a Polymerase Chain Reaction (PCR) apparatus for real-time detecting of one or more fluorescent signals. According to the apparatus, the PCR is performed by controlling heating and cooling intervals of a reagent container receiving space. With the aid of an added specific probe and fluorescent material, as well as a light source and a spectrometer, a generated fluorescent signal is detected. Meanwhile, the apparatus is also pre-loaded with an algorithm configured to analyze and quantify the fluorescent signal in a real-time manner.

PCR apparatus for real-time detecting of one or more fluorescent signals

What is disclosed in the present invention is to provide a quantitative transfer pipette structure, wherein an anti-backflow compartment is configured in the first bulb. The dimensions and locations of the first bulb, the second bulb and the third bulb are specifically configured to aspirate and transfer a specific volume of the liquid to a container, mix the liquid with the substance in the container by pressing and releasing the specific bulbs, so as to achieve the effects of precise quantification and sufficient mixing.

Quantitative transfer pipette structure

The present invention discloses a convective PCR apparatus by using a transparent conductive thin film to replace the traditional metal heater. The PCR reaction is activated when the container with reagents contacted the heated transparent conductive thin film and the temperature inside the container raised to initiate the convective circulation. Also, the present invention could apply for a quantitative PCR reaction by adding a specific probe, a fluorescent dye, a light source, or a photon receiver.

Convective PCR device

The present invention discloses an apparatus for performing PCR by thermal convection. The device includes a first bracket, a second bracket, a temperature sensing device, a power supplying device, a processor and an accommodation space. The device uses transparent conductive film to replace conventional thermostat metal stock to perform a heat process required in the PCR or RT-PCR process. The device further uses a reagent container whose bottom portion contacts the transparent conductive film and being heated by the transparent conductive film to establish a thermal circulation in the reagent container. The device can qualify or quantify the product of PCR or RT-PCR process by further incorporating specific probes, fluorescence material, light source, light receiver and light regulator.

Growing community of inventors

Taipei, Taiwan

Yu-Cheng Ou