Korea Institute of Science and Technology

Korea University Research and Business Foundation

Industry-university Cooperation Foundation Hanyang University

The Catholic University of Korea Industry-academic Cooperation Foundation

U & I Corporation

Yu Chan Kim

Hyun Kwang Seok

Myoung-Ryul Ok

Hojeong Jeon

Hyunseon Seo

Hyung-Seop Han

Eric Fleury

Jimin Park

Seung Hoon Um

So Yeon Kim

Seok Pil Lee

Jae Chul Lee

Kangwon Lee

Kyoung Won Park

InHo Kim

Seung Ja Oh

Jong Woong Park

Do Hyang Kim

Ho Young Park

Kwan Hyi Lee

Justin Jihong Chung

Yoon Ki Joung

Ki Bae Kim

Ji Hun Park

Ja Kyo Koo

Youngmin Seo

Choun Ki Joo

Byoung Chan Choi

Jae Ho Park

Ho Jeong Jeon

Jin Kyung Jeon

Jee-Wook Lee

Gayoung Jung

Hwa Chul Jung

Hyung Jin Roh

Myoung Ryul Ok

Jaekyun Kim

Yongwoo Chung

Won Hyun Shim

Indong Jun

Provided is a method of synthesizing apatite powder by emitting a laser beam to a surface of a substrate immersed in a precursor solution. The method is including immersing a substrate in an apatite-forming precursor solution, emitting a laser beam to a region on a surface of the substrate immersed in the precursor solution, and obtaining apatite powder generated in the precursor solution.

Method of synthesizing apatite powder using laser

Provided are phototherapeutic needle patches usable for phototherapy by using needle patches capable of injecting drugs or cosmetic substances to patients, and methods of manufacturing the same. A phototherapeutic needle patch may include a patch body attachable to skin of a patient, at least one microneedle protruding from the patch body, one end of the microneedle configured to deliver a drug through stratum corneum of the skin to inner tissues of the skin, and light grooves formed in a concave shape along a length direction of the microneedle in such a manner that therapeutic light radiated from a light source for phototherapy easily penetrates into the skin along the microneedle.

Phototherapeutic needle patches and methods of manufacturing the same

Provided is an implant having a controlled generation rate of reactive oxygen species and a method of controlling generation of reactive oxygen species using the same. The implant having a controlled generation rate of reactive oxygen species according to the present invention includes a body formed of a metallic material and having a groove, a first filling metal filling one region of the groove, and a second filling metal filling the groove on the first filling metal, wherein the second filling metal has an ionization tendency different from that of the first filling metal.

Implant having controlled generation rate of reactive oxygen species and method of controlling generation of reactive oxygen species using the same

Provided is a method for the selective differentiation into M1 macrophages under a pressurized environment, and more particularly, a method for the selective differentiation of undifferentiated macrophages into M1 macrophages, the method including incubating the undifferentiated macrophages in an incubator under the pressurized environment. In addition, provided is a method for producing osteoclasts, the method including: incubating undifferentiated macrophages in an incubator under a pressurized environment to differentiate into M1 macrophages; and differentiating the differentiated M1 macrophages into osteoclasts.

Method of selectively differentiating undifferentiated macrophage into M1 macrophage

Provided is an intraocular lens including: an optic portion; and a haptic portion extending from the optic portion, wherein a pattern having ridges and grooves is formed on at least one of the optic portion and the haptic portion, and each of the grooves has a nanostructure roughness. Provided also is a method of manufacturing an intraocular lens, the method including: seating an object to be processed including an optic portion and at least one haptic portion extending from the optic portion, processing a predetermined pattern for guiding cells by performing laser irradiation on the haptic portion and the optic portion, forming grooves having a nanostructure surface roughness in the predetermined pattern formed by laser beams, and the surface of each of the grooves has an average roughness Ra less than 200 nm.

Intraocular lens and method of manufacturing the same

Provided is a method of forming an apatite coating, the method including immersing a substrate in an apatite-forming precursor solution including Caions and POions, emitting a laser beam onto a surface of the substrate immersed in the precursor solution, and forming an apatite coating in a region exposed to the laser beam, wherein an output power of the laser beam is set within a range enabling the surface of the substrate to be melted.

Coating method of apatite using laser

The present disclosure relates to a biodegradable metal alloy with multiple properties, containing: 0.05-0.15 wt % of calcium; a metal element X having a HCP structure, of a composition not forming a precipitated phase when mixed with magnesium; and magnesium as the remainder.

Biodegradable metal alloy with multiple properties

There is provided an intraocular lens including an optic portion having a circular shape from one side thereof and including a first pattern which includes a ridge and a groove, and a plurality of haptic portions extending from an outer circumferential edge of the optic portion and each including a second pattern which includes a ridge and a groove, in which at least one of the ridges included in the first pattern and the second pattern and at least one of the grooves included in the first pattern and the second pattern includes a section in which a width is formed differently.

A cell patterning material, a method of preparing the cell patterning material, a cell patterning method using the cell patterning material, and a biosensor including patterned cells obtained by using the cell patterning method are provided. According to the present disclosure, cells may be conveniently and efficiently patterned and the time for applying external stimulation for patterning may be controlled. In addition, the patterned cells may have an excellent proliferation rate and excellent differentiation efficiency, and may be re-patterned in a different direction, and High-throughput screening using the patterned cells is possible.

Cell patterning material, preparation method thereof, and use thereof

A method for diagnosing a biomarker using magnetic particles and quantum dots for quantitative analysis and a biomarker diagnosis kit are provided. The method for diagnosing a biomarker includes: ii) providing magnetic particles having surfaces to which a primary antibody capable of collecting a biomarker using a linker is fixed; ii) providing quantum dots having surfaces to which a secondary antibody capable of detecting the biomarker is fixed; iii) sandwich-targeting the biomarker by the magnetic particles and the quantum dots; iv) selectively separating quantum dots sandwich-targeting the biomarker among the quantum dots; and v) quantifying the concentration of the biomarker by measuring absorbance or intensity of fluorescence of separated quantum dots.

Method for diagnosing biomarkers and biomarker diagnosis kit

In Cu-based bulk amorphous matrix composite materials, comprising a Cu-based amorphous alloy containing high fusion point element(s) selected from a group of Ta, W or combination thereof, wherein the high fusion point element(s) has(have) a shape of crystalline grain and is(are) dispersed around a Cu-based amorphous matrix. Cu-based bulk amorphous matrix composite materials have the composition expressed as the following Chemical formula 1;CuZrTiR&#x2003;&#x2003;[Chemical formula 1]

Method for producing composite materials comprising Cu-based amorphous alloy and high fusion point element and composite materials produced by the method

The present invention relates to a Cu-based amorphous alloy composition having a chemical composition represented by the following general formula, by atomic %: CuZrAl(M)(M), where a, b, c and d satisfy the formulas of 36&#x2266;a&#x2266;49, 1&#x2266;b&#x2266;10, 0&#x2266;c&#x2266;10, and 0&#x2266;d&#x2266;5, respectively, and c and d are not zero at the same time, and M, the 4th element added to a ternary alloy of Cu&#x2014;Zr&#x2014;Al, is one metal element selected from the group consisting of Nb, Ti, Be and Ag, and M, the 5th element added to the ternary alloy of the Cu&#x2014;Zr&#x2014;Al, is one amphoteric element or non-metal element selected from the group consisting of Sn and Si.

Cu-based amorphous alloy composition

Growing community of inventors

Goyang-si, South Korea

Yu Chan Kim