Chang Gung University

Chang Gung Memorial Hospital, Linkou

Yu-An Kung

Shin-Ru Shih

Chuan-Tien Hung

Sheng-Yu Huang

Peng-Nien Huang

Yu-Nong Gong

Chih-Ching Wu

Chiung-Guei Huang

Chung-Guei Huang

Huan-Jung Chiang

Rei-Lin Kuo

Kar-Yee Yu

Hsin-Ping Chiu

Hou-Chen Lee

Guang-Wu Chen

Kuan-Ting Liu

A method for determining immune competence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) includes obtaining a blood sample from a subject in need thereof, detecting, in the blood sample, levels of binding antibodies against SARS-CoV-2 spike S1 protein and its receptor binding domain (RBD), and calculating a weighted value using a regression model. Another method for determining immune competence against SARS-CoV-2 is also disclosed.

Method for determining immune competence against severe acute respiratory syndrome coronavirus 2

Disclosed herein is a method for inhibiting virus infection, including administering to a subject in need thereof an effective amount of a ferroptosis inhibitor or a pharmaceutically acceptable salt thereof. Also disclosed is a method for inhibiting viral replication, including contacting a virus with a ferroptosis inhibitor or a pharmaceutically acceptable salt thereof.

Method for inhibiting virus infection and replication

Disclosed herein are recombinant polypeptides derived from FBP1 and FBP2. Also disclosed herein are recombinant expression vectors and recombinant host cells for producing the aforesaid recombinant polypeptides. The recombinant polypeptides are proven to be useful and effective in producing a picornavirus with a type I internal ribosome entry site (IRES), so as to facilitate the preparation of a viral vaccine.

Recombinant polypeptides derived from FBP1 and FBP2 and uses of the same

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Taoyuan, Taiwan

Yu-An Kung