Institute of Pharmacology and Toxicology Academy of Military Medical Sciences Pla China

Xiaomi Inc.

Institute of Pharmacology

Toxicology Academy of Military Medical Sciences P.l.a., China

Beijing Xiaomi Mobile Software Co., Ltd.

Youzhi Zhang

Nan Zhao

Yunfeng Li

Liuhong Yun

Rui Xue

Rifang Yang

Hongxia Chen

Yongzhen Li

Juanjuan Qin

Peng Li

Cheng Zhang

Yanping Zhang

Zhigang Li

Bohua Zhong

Xinhua He

Jinbin Lin

Rusheng Zhao

Jixi Luo

Li Yuan

Zhenzhen Wang

Meiying Li

Zhongyao Feng

Zengliang Jin

Xiaodan Xu

Jiazhi Yao

Jin Shang

Zengling Jin

A method for changing an emoticon in a chat interface is disclosed. The method may be implemented by a terminal device. The method may comprise detecting whether a message received by the terminal device contains a first changeable emoticon, checking a first emoticon-value list to determine a first value corresponding to the first changeable emoticon, if the received instant message contains the first changeable emoticon, checking a second emoticon-value list to determine a second value corresponding to a second emoticon, the second emoticon being configured to change the first changeable emoticon, adding the first value and the second value to obtain a value result, and checking the first emoticon-value list to change the first changeable emoticon to another emoticon corresponding to the value result.

Method and device for changing emoticons in a chat interface

Disclosed are 2-arylimidazo[1,2-a]pyridine-3-acetamide derivatives represented by formula I, their tautomer, racemate or optical isomer, their pharmaceutically acceptable salt, or their solvates, wherein R, R, Rand Rare defined as in the specification. Preparation methods of said compounds and use of said compounds in treating and/or preventing central nervous system disease associated with TSPO functional disorder 

2-aryl imidazo[1,2-a]pyridine-3-acetamide derivatives, preparation methods and uses thereof

Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof.  The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.

1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof

The present invention relates to a new amine compound or a pharmaceutically acceptable salt thereof, wherein the definitions of X, R, Rand n are given in the description, to a pharmaceutical composition containing the compound as active ingredient, and to use of the amine compound or its pharmaceutically acceptable salt for the manufacture of an anti-depressent drug. 

Amine compounds and medical uses thereof

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Beijing, China

Youzhi Zhang