Seikagaku Corporation

Yousuke Yasuda

Kenji Miyamoto

Hideo Mochizuki

Satoshi Miyauchi

Masami Iida

Akira Tawada

Junichi Onaya

Yuji Matsuzaki

Keiji Yoshioka

Yusuke Hori

A polysaccharide derivative having a high solubility in an aqueous solvent is produced. The production method of the present invention uses a compound shown by the general formula (1) as a condensing agent and allows a polysaccharide having a carboxyl group to react with an an organic compound having a functional group capable of condensing with the carboxyl group to prepare the polysaccharide derivative:  

Method of producing polysaccharide derivatives

A drug-introduced photo-crosslinked hyaluronic acid derived gel which is a photo-crosslinked hyaluronic acid gel into which a drug is introduced through a covalent bond, and has characteristics that are capable of extruding from an injection device. The drug-introduced photo-cross-linked hyaluronic acid derived gel is capable of extruding, for example, by an injection needle of 20 to 25 gauge with a pressure of 0.5 to 5 kg/cm.

Drug-introduced photo-crosslinked hyaluronic acid derived gel

A hyaluronic acid derivative in which an anti-inflammatory drug is bound to hyaluronic acid through a covalent bond via a spacer having a biodegradable region, and a production process thereof.

Hyaluronic acid derivative and drug containing the same

Method for producing oligosaccharide, and novel oligosaccharide and pharmaceutical composition containing the same

Growing community of inventors

Higashiyamato, Japan

Yousuke Yasuda