Symetis Sa

Dna Genotek Inc.

Boston Scientific Corporation

Baylis Medical Company Inc.

Abogen, Inc.

Other

Boston Scientific Scimed, Inc.

Anchor Orthopedics Xt Inc.

Xeltis Ag

Xetis Ag

Youssef Biadillah

Jean-Luc Hefti

Fabien Lombardi

Stephane Delaloye

Luc Mantanus

Jacques Essinger

Stephen Douglas Andrews

Stéphane Delaloye

Pierre Simonin

Gareth Davies

Amanda April Hartley

Naheed Visram

Taras Juzkiw

Lionel Flaction

Neil Godara

Martijn Antonius Johannes Cox

Arnaud Humair

Bryce G Rutter

John Paul Urbanski

Melvin Joshua Leedle

Benjamin Cooper Priess

Jonathan Sundy

Jean-luc Hefti

Yutit Wanakoht

Reynald Passerini

Chris Briden

David S Frank

John R Zeman

Charles T Tackney

Manasi Jain

Iker Mallabiabarrena

Michael Paris

Various embodiments of a seal for a stent-valve, and methods of production, are described. In some embodiments, the seal or a skirt comprises a fabric wall portion and a polymeric material fused to the fabric wall portion, the polymeric material having a melting temperature that is lower than that of the fabric wall portion. The fibres of the fabric may remain unmelted at the interface with the polymeric material, the polymeric material being attached to material to the fibres of the fabric wall portion by fusion. The polymeric material may provide a welded joint to another fabric wall portion and/or may reinforce the fabric and/or may occlude pores of the fabric.

Stent seals and method of production

Apparatus () for compressing a transcatheter cardiac stent-valve () comprises: a first compressor stage () including a hollow channel () with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage () comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.

Method and apparatus for compressing/loading stent-valves

A solution is described for preserving cells and/or extra-cellular components in naturally expressed bodily fluids (e.g. saliva, sputum, urine) for further downstream analysis and/or for diagnosis of a medical condition. The solution may be hypertonic with respect to blood. Techniques are described for enriching cells from a sample of a naturally expressed bodily fluid, and/or for analysis, e.g. to diagnose medical conditions such as cancer, obesity, infections, autism, Alzheimer disease, hetotological disorders, cardiovascular disease or disorders, diabetes, vulnerable plack, LTBI, HIV infection, COPD, ACQS.

Devices, solutions and methods for sample collection related applications, analysis and diagnosis

Bioabsorbable medical devices such as vascular closures, mitral chorea replacements, and mitral leaflet extensions are provided.

Medical device using bioabsorbable material

A delivery catheter for a prosthetic heart valve, the valve expandable from a collapsed condition for delivery to an expanded condition for implantation, the delivery catheter comprising: a holder for engaging the valve in the collapsed state of the valve, the holder configured such that (i) in response to a radial compression force exerted thereon, the holder has a first shape defining an exposed engagement region for engaging at least a portion of the collapsed prosthetic heart valve for restraining axial displacement of the prosthetic valve in at least one axial direction of the catheter, and (ii) in response to removal of the radial compression force upon expansion of the valve, at least a portion of the holder transitions to a second shape.

Prosthetic valve. delivery apparatus and delivery method

The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g., saliva, urine), which can then be subjected to processing to extract a plurality of cells. The plurality of cells can be further processed to isolate one and/or another cell type therefrom. The plurality of cells, as well as the isolated cell type(s), can be analyzed for functional genomic and epigenetic studies, as well as biomarker discovery.

Method for collecting and preserving a biological sample

Cell preserving solution

Biological collection system

A delivery catheter () for a stent valve (), the delivery catheter having a distal portion () insertable into an anatomy, the distal portion comprising an accommodation region () for accommodating a stent-valve for delivery into the anatomy, the delivery catheter further comprising at least one sheath () that is translatable between a closed position for at least partly closing the accommodation region and an open position for at least partly opening the accommodation region.

Stent valve, delivery apparatus and method therefor

Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.

Transcatheter stent-valves and methods, systems and devices for addressing para-valve leakage

Devices, solutions and methods for sample collection

A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.

Transcatheter stent-valves

Growing community of inventors

Lausanne, Switzerland

Youssef Biadillah