Wake Forest University

University of California

Youngkyoo Jung

Eric C Wong

Thomas T Liu

Jeongchul Kim

Christopher T Whitlow

Kun Lu

Post-image acquisition methods, circuits and systems for evaluating medical images of a subject register a region of interest in a first medical image taken at a first point in time to the region of interest in a second image taken before or after the first medical image with voxels from the first and second medical images having a voxel-wise correspondence. The methods, circuits and systems can use line and/or shape changes of defined 3-D finite elements to electronically determine directional, shear and volumetric changes of the voxels in the region of interest between the first and second medical images.

Medical image analysis using mechanical deformation information

Methods, systems, computer programs, circuits and workstations are configured to generate at least one two-dimensional weighted CBF territory map of color-coded source artery locations using an automated vascular segmentation process to identify source locations using mutual connectivity in both image and label space.

Vascular territory segmentation using mutual clustering information from image space and label space

Methods, systems, computer programs, circuits and workstations are configured to generate at least one two-dimensional color blood flow map that combines X and Y encoded primary and secondary peak data of 1-dimensional Inverse Fourier Transform images to visually indicate (i) anterior/posterior and right/left directional components of respective feeding arteries using defined colors and (ii) brightness to indicate an amount of blood flow associated with each voxel, with increased brightness associated with increased blood flow.

Vessel encoded arterial spin labeling using fourier encoding suitable for vascular territory mapping

Techniques, systems and apparatus are described for magnetic resonance imaging. A magnetic resonance imaging (MRI) system comprises a scanner comprising a magnet, gradient coils and a radio frequency (RF) system to perform various operations. The scanner can apply a gradient field and a train of RF pulses comprising more than two phases to tag a target blood vessel, and acquire magnetic resonance signals based on the applied train of RF pulses to sample the more than two phases. The MRI system includes a data processing system in communication with the scanner to receive the acquired magnetic resonance signals and process the received magnetic resonance signal to generate images proportional to perfusion.

Multi-phase pseudo-continuous arterial spin labeling

Techniques and systems are disclosed for measuring arterial transit delay using pseudo- continuous arterial spin labeling (ASL) with variable TR and interleaved post-labeling delays. In one aspect, a magnetic resonance imaging method for measure arterial blood flow and transit delay using arterial spin labeling (ASL) includes applying an ASL pulse sequence. The ASL pulse sequence includes a pre- saturation pulse, and a labeling pulse. The method includes performing data acquisition to measure a transit delay, which represents a time needed for labeled blood to arrive in an imaging slice.

Growing community of inventors

Winston-Salem, NC, United States of America

Youngkyoo Jung