Florida International University

Youngjin Jung

Anuradha Godavarty

Jean Gonzalez

The present application describes techniques to image biological tissue to determine biological information of an imaged tissue sample such as changes in hemoglobin concentrations, blood flow rate (pulse), and/or spatio-temporal features. Embodiments include illuminating the tissue sample with light in the near-infrared (NIR) spectrum, which is minimally absorbed but scattered through the tissue sample. By detecting the NIR light that is attenuated through, transmitted through, and/or reflected off the tissue to be imaged, the resulting NIR intensity signals may be further analyzed to provide this data. Embodiments include using multiple NIR light sources having varying wavelengths to obtain changes in the oxy- and deoxy-hemoglobin concentrations of the imaged tissue region. The tissue sample may be imaged over a time period, and the NIR images may be viewed statically or in real time after post-processing analyses have been performed.

Near-infrared optical imaging system for hemodynamic imaging, pulse monitoring, and mapping spatio-temporal features

A method, apparatus, and system acquire data to create a 3D mesh representing a 3D object. The method, apparatus, and system acquire image data of the 3D object using an imaging probe that includes illumination and detection capability. A light source operates to illuminate the 3D object for reflection and/or trans-illumination imaging, and a detection assembly receives image reflection and/or trans-illumination image data. The reflectance and trans-illumination image data collected by the detection assembly are co-registered with a previously acquired 3D mesh using data from a tracking system monitoring the position of the probe, displayed in real-time, and optionally saved.

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Miami, FL, United States of America

Youngjin Jung