Y-biologics Inc.

Intocell, Inc.

Youngja Song

Young Woo Park

Jae Eun Park

Bum-chan Park

Seok Ho Yoo

Ji-Young Shin

Sunha Yoon

Yunseon Choi

Sang Pil Lee

Sung Ho Woo

Hyang Sook Lee

Sunyoung Kim

Jaeho Lee

Doohwan Jung

Taekyo Park

Jongun Cho

Donghoon Seo

Sangkwang Lee

Sanghyeon Yun

Beomseok Seo

Okku Park

Suho Park

Ji Su Lee

Young-Gyu Cho

Sena Kim

Minah Seol

Hyun Ju Lee

Jung Chae Lim

Si Hyung Lee

Gi Sun Baek

Yeung Chul Kim

Hyun Mi Lee

Jisu Lee

Yosup Rew

Jina Song

Jihyeon Ha

Eun-Young Shim

Dong Jung Lee

Yunjung Ko

Yeung-Chul Kim

Eunjin Lee

Minju Lee

Gisun Baek

The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.

Antibody-drug conjugates comprising anti-B7-H3 antibodies

A monoclonal antibody or an antigen-binding fragment thereof according to an embodiment of the present invention can bind to lymphocyte-activation gene 3 (LAG-3) including a heavy chain variable region and a light chain variable region and inhibit the activity thereof. Thus it is expected to be useful for the development of immunotherapeutic agents for various disorders that are associated with LAG-3.

Monoclonal antibody specifically binding to LAG-3 and use thereof

The present invention relates to an antibody against delta-like 1 homolog () (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, an antibody drug conjugate (ADC) comprising the same, a pharmaceutical composition for treating cancer, a composition for diagnosing cancer, and a chimeric antigen receptor (CAR) and a T-cell engager comprising the same.

Antibody against human DLK1 and use thereof

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Daejeon, South Korea

Youngja Song