Korea Research Institute of Chemical Technology

Kt&g Corporation

Young-Sook Kim

Young Kwan Ko

Gyu Hwan Yon

Dong Jin Park

You-Hui Lee

Bong-Jin Kim

Jae-Hak Kim

Chang Jin Kim

Jung Sup Choi

Sung-Su Lim

Eun-Mi Bae

Yu-Sung Jun

Cheol-Hae Lee

Dong-Ha Lee

Kyung-Sook Kim

Hyun-Kyoung Kim

Soon-Ok Baik

Yoon Jung Ju

Boyoung Lee

Disclosed herein is a composition containing a novel strainKR-001 strain or a culture broth thereof as an active ingredient for weed control. More particularly, theKR-001 strain of the present invention, culture broth thereof, or culture fraction shows an excellent weed-killing ability on grass weeds, broadleaf weeds, and hard-to-control weeds, and a medium composition containing a carbon source and a nitrogen source in an optimal condition may significantly increase yield of an active material produced by the strain with low cost. Therefore, the strain can be usefully employed to a herbicide composition for weed control and a method for weed control.

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The present invention provides a crude drug composition comprising extracts of radish and tea leaf and additionally comprising an extract extracted from at least one crude drug selected from a group consisting ofvarPericapium,Pericarpium,L.,L.,and. Inventive composition induces the functional activation of intestine in the charcoal-administered animal model experiment and constipation-induced animal model and improves the constipation by activating mucus secretion in the intestine. And the composition is confirmed to inhibit the growth of intestinal harmful bacteria without affecting the growth of beneficial bacteria. Therefore, the crude drug composition of the present invention may be useful for the pharmaceutical composition and health care food for preventing, alleviating and treating intestinal disease and constipation.

Crude drug compositions and the process for preparing them

A .beta.-methylcarbapenem compound of formula (I), a salt or an ester thereof, a process for the preparation thereof and a anti-bacterial composition containing same: ##STR1## wherein: R.sup.1 is a C.sub.1-6 alkyl, C.sub.2-6 alkenyl, cycloalkyl, aryl or heterocyclic aryl group.

.beta.-methylcarbapenem derivatives, process for the preparation thereof

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Daejeon, South Korea

Young-Sook Kim