Samsung Electronics Co., Ltd.

Chungnam National University Industry Foundation

Young-nam Kwon

Young-a Kim

Jeong-gun Lee

Myo-yong Lee

Yeon-ja Cho

Shin-i Yoo

In-Ho Lee

Chang-eun Yoo

Young-Hoon Kim

Soo-suk Lee

Won-Cheol Jung

In-jae Lee

Kwang-ho Cheong

Jang-seok Ma

Fu Wang

Bum-jae Lee

Seung-yeon Yang

Jong-seop Lee

Joong-gun Lee

Hui-jun Sim

Young-hwan Lee

Tae-jung Kim

Provided are hydrophobic layer formed by polymer represented by Formula 1 below and has a weight average molecular weight of about 10,000 to about 500,000 g/mol, hydrophobic layer including the polymer and an electronic articles including the hydrophobic layer: 

Polymer for forming hydrophobic layer, hydrophobic layer comprising the polymer and electronic article comprising the hydrophobic layer

A method and apparatus for a rapid disruption of cells or viruses using micro magnetic beads and a laser are provided. According to the method and apparatus for a rapid disruption of cells or viruses using micro magnetic beads and a laser, cell lysis within 40 seconds is possible, the apparatus can be miniaturized using a laser diode, a DNA purification step can be directly performed after a disruption of cells or viruses, and a solution containing DNA can be transferred to a subsequent step after cell debris and beads to which inhibitors of a subsequent reaction are attached are removed with an electromagnet. In addition, by means of the cell lysis chip, an evaporation problem is solved, vibrations can be efficiently transferred to cells through magnetic beads, a microfluidics problem on a rough surface is solved by hydrophobically treating the inner surface of the chip, and the cell lysis chip can be applied to LOC.

Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser

Provided are methods of isolating and amplifying nucleic acids from and in a nucleic acid-containing sample. The nucleic acid isolation method includes contacting a nucleic acid-containing sample to a silanized solid support to capture nucleic acids to the silanized solid support and treating the nucleic acid-captured solid support with an alkaline solution of pH 9 to 14. The nucleic acid amplification method includes contacting a nucleic acid-containing sample to a silanized solid support to capture nucleic acids to the silanized solid support; treating the nucleic acid-captured solid support with an alkaline solution of pH 9 to 14; and adding a nucleic acid amplification solution to the resultant solution after the alkaline solution treatment to perform nucleic acid amplification.

Methods of isolating and amplifying nucleic acids using silanized solid support

An apparatus and method for purification of nucleic acids of cells or viruses are provided. The nucleic acid purification apparatus includes: a cell lysis capillary having a sample inlet through which samples and magnetic beads are introduced; a vibrator attached to the capillary and mixing the samples and the magnetic beads in the capillary; a laser generator attached to the capillary and supplying a laser to the capillary; and a magnetic force generator attached to the capillary and fixing the magnetic beads to a capillary wall. According to the method and apparatus, PCR yield can be increased since PCR inhibitors can be readily removed by means of a phase separation in a capillary. The use of an electromagnet ensures the removal of the PCR inhibitors. In addition, since cell lysis and DNA purification process can be simultaneously performed, LOC steps can be reduced.

Method for purification of nucleic acids by phase separation using laser and beads

An optical detection device for biochemically analyzing samples of microfluidic chips such as DNA chips or protein chips is provided. The optical detection device includes a light source for generating excitation light to excite a sample, a detection plate having an optical waveguide with the sample mounted thereon, a linear symmetry lens for shaping the excitation light into a desired shape having a uniform intensity distribution and transmitting it to the detection plate, and a detector for detecting radiation from the sample.

Optical detection device

Growing community of inventors

Gyeonggi-do, South Korea

Young-nam Kwon