Korea Research Institute of Bioscience and Biotechnology

Bioleaders Corporation

Kookmin University

The Industry & Academic Cooperation in Chungnam National University

Chungbuk National University Industry Academic Cooperation

Young-Ki Choi

Moon-Hee Sung

Haryoung Poo

Chul Joong Kim

Yong Taik Lim

Il Ha Lee

Sang-Mu Shim

Dong Jin Jeong

Dai-Won Yoo

The present invention relates to an adjuvant composition containing poly-gamma-glutamic acid-chitosan nanoparticles and a vaccine composition containing the adjuvant composition, and more particularly to an adjuvant composition containing nanoparticles prepared by ionic bonding between poly-gamma-glutamic acid having ensured safety and chitosan, and a vaccine composition containing the poly-gamma-glutamic acid-chitosan nanoparticles and an antigen. The adjuvant containing the poly-gamma-glutamic acid-chitosan nanoparticles has little or no toxicity and side effects and is added to human or animal vaccines for the prevention and treatment of viral and bacterial infections and cancers to increase the production of antibodies.

Adjuvant composition containing poly-gamma-glutamic acid-chitosan nanoparticles

The present invention relates to a pharmaceutical composition for inhibiting or preventing viral infection, which comprises an effective dose of poly-gamma-glutamic acid (&#x3b3;-PGA), and more particularly, to a pharmaceutical composition, a functional food, and a feedstuff additive capable of inhibiting viral infection and preventing viral diseases, which comprise poly-gamma-glutamic acid having an infection-inhibiting effect against viruses, such as an influenza virus, inducing respiratory infection or systemic infection, as an effective ingredient. The composition containing poly-gamma-glutamic acid as an effective ingredient according to the present invention, is effective for use as an animal feedstuff additive or a pharmaceutical agent for preventing influenza virus infection and various viral diseases as well as a pharmaceutical composition and a functional food to promote human health.

Composition for preventing virus infection comprising poly-gamma-glutamic acid

Growing community of inventors

Cheongju-si, South Korea

Young-Ki Choi