University of Pennsylvania

Young-Joo Lee

Shu Yang

Randall D Kamien

Michael David Tanis

Hyesung Cho

Jason Christopher Jolly

Suhail K Kanchwala

Eric Jablonka

Provided are intraoperative devices, the devices comprising a substrate having a plurality of discontinuous cuts formed therein, the plurality of discontinuous cuts being formed such that when the substrate is subjected to deformation, the substrate is capable of deformation beyond an initial state so as to achieve a first shaped three-dimensional state. Through design of the cut patterns in 2D, one can locally control the stretchability and elasticity within the substrate. The substrate can then be deformed into a 3D structure that can provide shape and support to reconstructed tissue in the desired regions while also minimizing operative time and cost. Also provided are related methods of using the disclosed devices; the devices can be used in autologous tissue donation procedures as well as prosthetic procedures.

Kirigami modification of biomedical tissue reinforcing meshes and matrices for expansile two-to-three dimensional conversion

Growing community of inventors

Philadelphia, PA, United States of America

Young-Joo Lee