Cj Cheiljedang Corporation

Cj Corporation

Cj Cheiledang Corporation

Young-Hoon Park

Hyun-Soo Kim

So-Young Kim

Jin-Ho Lee

Hyo-Jin Kim

Hyang Choi

Jeong-Hwan Kim

Jae-Ick Sim

Sang-Jo Lim

Yoon-Suk Oh

Jea-Young Chang

Eun-Sung Koh

Whan-Koo Kang

Hye-Jin Choi

Ki-Hoon Oh

Seong-Jun Kim

Jae-Yeong Ju

Young-Hyeon Kwag

Kwang-ho Lee

Jong-Soo Choi

Sung-Sik Park

Yong-Uk Shin

Bheong-Uk Lee

So-Yeon Rah

Hye-Won Kim

Eun Sung Koh

Jae-woo Jang

Jae Yeong Ju

Jae-Woo Jang

Jin-hyun Kim

Jin-Sook Chang

Jun-Ok Moon

Kyung-oh Choi

Jin-nam Lee

Soo-Youn Hwang

Hyung-Joon Kim

Sun-Young Lee

Sung-Oh Chung

Young-wook Cho

Ji-sun Lee

Jong-Kwon Han

Sung Oh Chung

Hyoung-suk Kim

Mun-Su Rhee

Kwang-Myung Cho

Seong-Uk Kang

Mi-Hae Cho

Jang-Hee Park

Young-Lyeol Yang

Ho-Soo Lim

Jin-Nam Lee

Jin-Su Chung

Bheonk-Uk Lee

Ko-hoon Oh

Yoon-suk Oh

Jae-ick Sim

Tae-Sun Kang

Won-Sik Lee

Byoung-Hoon Kim

Seong-Jun 307-1001 Pungnimsinan Apt Kim

Dae-Cheol 201-302 Hwanggolmaeulsinmyeong Apt Kim

Hyun-Min Koo

Hye-Won Um

Hee-Jong Lee

Chang-Hyun Jin

Disclosed is a polynucleotide encoding &#x3b3;-butyrobetaine hydroxylate (&#x3b3;-BBH) originating from. Also disclosed are a recombinant vector comprising the polynucleotide, a transformant transformed with the recombinant vector, &#x3b3;-BBH encoded by the polynucleotide, and a method of preparing L-carnitine, which comprises hydroxylating &#x3b3;-butyrobetaine using &#x3b3;-BBH encoded by the polynucleotide.

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The present invention relates to a microorganism ofssp. having enhanced expression of gene for encoding molybdenum cofactor biosynthesis enzyme A and a method for producing L-lysine using the same, which has effects on providing the production method of L-lysine using thestrain having enhanced productivity of L-lysine by intensifying expression of the moaA gene for encoding molybdnum cofactor biosynthesis enzyme A.

Provided are a novel promoter nucleic acid molecule having a nucleotide sequence of SEQ ID NO: 1 or 2 derived from, a recombinant vector comprising the promoter, a host cell transformed with the vector and a method of expressing genes of interest using the host cell.

Promoter nucleic acid molecule derived from corynebacterium glutamicum, recombinant vector comprising the promoter, host cell comprising the recombinant vector and method of expressing gene using the host cell

Provided is a microorganism belonging to the family Enterobacteriaceae including: a polynucleotide encoding N-trimethyllysine hydroxylase activity derived from; a polynucleotide encoding 3-hydroxy-6-N-trimethyllysine aldolase activity derived from; a polynucleotide encoding &#x3b3;-trimethylaminoaldehyde dehydrogenase activity derived from; and a polynucleotide encoding &#x3b3;-butyrobetaine hydroxylase activity derived from. Provided is also a process for producing L-carnitine using the microorganism.

The present invention relates to a preparation method of an L-threonine producing strain by utilizing a novel L-threonine importer identified from. The method can be advantageously used for the production of L-threonine by increasing the fermentation concentration of Lthreonine and the yield per unit thereof.

Provided are mutant strains derived fromsp. GPU1114 (Accession No. KCCM-10536), having cumulative inactivation of deoD, aphA, appA, and hprt genes, and methods of using the same.

Escherichia strain capable of converting XMP to GMP and maintaining the inactivated state of gene(s) associated with GMP degradation and methods of using the same

Provided is a microorganism that belongs to Enterobacteriacae and a method of producing L-carnitine using the same. The microorganism includes polynucleotide encoding activity of S-adenosylmethionine-6-N-iysine methyltransferase from Neurospora crassa, polynucleotide encoding activity of 6-N-trimethyllysine hydroxylase, polynucleotide encoding activity of 3-hydroxy-6-N-trimethyllysine aldolase, and polynucleotide encoding activity of &#x3b3;-trimethylaminoaldehyde dehydrogenase and y-butyrobetaine hydroxylase.

Provided are a promoter including at least one polynucleotide selected from the group consisting of SEQ ID NOS: 1 to 7, an expression cassette including the same, a vector including the expression cassette, a host cell including the vector, and a method of expressing a gene using the host cell.

The present invention relates to a Tryptophan-producingmutant strain CJ285 (KCCM-10534) containing single or multi mutant genes related with Tryptophan biosynthesis and production method of Tryptophan using the same. More particularly, DNA base sequences and amino acid sequences aroF, aroG, trpR, and tyrR originated from tryptophan producingmutant strain CJ285 (KCCM-10534) and related with Tryptophan biosynthesis, are disclosed, andCJ285 containing at least one of the mutant genes is cultivated directly in a glucose-containing fermentation medium, whereby L-tryptophan can be accumulated in the culture medium.

The invention relates to a microorganism, obtained by treatingKCCM 10488 producing 5'-Xanthylic acid as parent strain with UV radiation and mutation Derivatives such as N-methyl-N&#x2032;nitro-N-nitrosoguanidine (NTG), Having a resistance to 5-fluorotryptophan which enhances Biosynthesis of N5-N10-tetrahydrofolate used for transferring Two formyl group during the process of puring biosynthesis, making It possible to accumulate 5&#x2032;xanthylic acid in culture medium at a high Yield and high concentration rate same period of fermentation.

Microorganism producing 5'-xanthylic acid

Provided is S-adenosylmethionine-6-N-lysine-methyl-transferase obtained from, a polynucleotide encoding the same, a vector and host cell containing the polynucleotide, and a method of producing trimethyllysine by culturing the host cell.

Provided are anspecies microorganism andspecies microorganism that are transformed with a foreign NADP dependent glyceraldehydes-3-phosphate dehydrogenase gene and have the ability to produce L-lysine and a method of producing L-lysine using the microorganisms.

A method of isolating 1,3-propanediol from a solution containing 1,3-propanediol, 1,2-propanediol, glycerol, and glucose is provided. The method includes: obtaining a concentrate by concentrating the solution via reduced pressure evaporation; dissolving the concentrate in a solvent selected from the group consisting of ethyl acetate, methyl ethyl ketone, and a mixture thereof and leaving the solution alone to fractionate the compounds in a solvent layer and a water layer; and loading the solvent layer in a silica-filled column under a low pressure liquid chromatography condition and eluting the solvent layer with a mixed solvent of methanol and at least one solvent which is miscible with methanol and has a polarity lower than methanol.

Method of isolating 1,3-propanediol or 1,3-propanediol and 1,2-propanediol from solution containing 1,3-propanediol, 1,2-propanediol, glycerol, and glucose

The invention relates toCJXSP 0201 KCCM 10448 producing 5'-xanthylic acid. More specifically, the invention relates toCJXSP 0201 KCCM 10448 which is a mutant strain ofKCCM 10340 having a resistance to osmotic pressure. In order to obtain mutant strain having enhanced respiratory activity, the present invention adoptedKCCM 10340 as parent strain and treated it with UV radiation and mutation derivatives such as N-methyl-N&#x2032;-nitro-n-nitrosoguanidine (NTG) according to ordinary procedure. Therefore,CJXSP 0201 KCCM 10448 of the present invention makes it possible to overcome growth-standing phase rapidly on early culture and for same period of fermentation, can accumulate 5&#x2032;-xanthylic acid in culture medium at a high yield and concentration rate.

The invention relates toCJXOL 0201 KCCM 10447 producing 5'-xanthylic acid. More specifically, the invention relates toCJXOL 0201 KCCM 10447 which is a mutant strain ofKCCM 10340 having a resistance to oligomycin. In order to obtain mutant strain having enhanced respiratory activity, the present invention adoptedKCCM 10340 as parent strain and treated it with UV radiation and mutation derivatives such as N-methyl-N&#x2032;-nitro-n-nitrosoguanidine(NTG) according to ordinary procedure. Therefore,CJXOL 0201 KCCM 10447 of the present invention makes it possible to increase ATP reproducing activity for same period of fermentation and can accumulate 5&#x2032;xanthylic acid in culture medium at a high yield and concentration rate.

Microorganism producing 5'xanthylic acid

Growing community of inventors

Seongnam, South Korea

Young-Hoon Park