Abion Inc.

Seoul National University

Young Deug Kim, I

Young Kee Shin

Jun Young Choi

Ji Hye Lee

Sung Su Kim

Sung Youl Hong

Ha Yeon Park

Heo Bin Yang

The present invention relates to an anti-c-Met agonist antibody and use thereof, and more particularly, to an agonist antibody or fragment thereof that specifically binds to a human-derived c-Met protein, to a method for producing the same, to c-Met specific detection method using this, to a composition for preventing or treating cancer comprising the same, to a composition for inducing stem cell differentiation, and a culture medium for stem cells. The method of the present invention can be usefully used for detecting c-Met antibodies, inducing stem cell differentiation using the antibody, and treating or preventing cancer.

Anti-c-Met agonist antibody and use thereof

The invention of the present application relates to a use of an antibody binding specifically to ECL-2 of claudin 3 and functional fragments thereof in cancer cell detection, diagnosis, imaging, and application to cancer treatment (anticancer use of the antibody itself, and application to ADC and CAR-expression cells (particularly immune cells)), an antibody that includes a characteristic CDR sequence exerting a remarkable effect in such uses, and a functional fragment thereof.

Antibody binding specifically to ECL-2 of claudin 3, fragment thereof, and use thereof

Growing community of inventors

Seoul, South Korea

Young Deug Kim, I