Postech Academy-industry Foundation

Ulsan National Institute of Science and Technology

Korea Food & Drug Administration

Unist, Inc.

Young Chan Chae

Jong Hun Im

Jung Hwan Lee

Jong In Kim

Sung Ho Ryu

Sung Key Jang

Hyungu Kang

Ki Seok Kim

Hye Jung Lee

Mi-Jin Kwon

Soon Hag Kim

Youndong Kim

Sun Hak Lee

Eun Jung Jang

Pann-Ghill Suh

Won Jun Kang

Yu Jin Lee

Il Ung Oh

Min Jeong Choi

Ii Shin Kim

Youn Dong Kim

Youngdong Kim

Il Shin Kim

This disclosure relates to DNA aptamer specifically binding to periostin, which is cancer-related protein, a composition for inhibiting cancer and/or cancer metastasis and/or a composition for diagnosis of cancer and/or cancer metastasis, comprising the same as an active ingredient, wherein the aptamer has different binding mechanism from the existing antibodies, and thus, may inhibit and diagnose cancer/cancer metastasis more effectively.

Aptamer for periostin and anti-cancer composition including same

Disclosed are a DNA aptamer specifically binding to the Her2 (ERBB2) receptor involved in the onset of breast cancer, a composition for the suppression of cancer metastasis comprising the same as an active ingredient, and a composition for the diagnosis of cancer comprising the same as an active ingredient. Due to its binding mechanism being different from that of the conventional antibody, the aptamer can be effectively used for suppressing cancer metastasis and diagnosing cancer.

Aptamer which selectively binds to ERBB2 receptor and uses thereof

Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.

Method of diagnosing cancer using a nucleolin specific aptamer

Method of treating hyperproliferation of cells using a nucleolin specific aptamer

Growing community of inventors

Pohang-si, South Korea

Young Chan Chae