Daewoong Pharmaceutical Co., Ltd.

Youn Jung Yoon

Joon Seok Park

Min Hee Cho

Ho Bin Lee

Ja Kyung Yoo

Min Jae Cho

Ji Duck Kim

Deok Ki Eom

Mi Ryeong Han

Keuk Chan Bang

Chang Min Park

Bong Yong Lee

Keuk-Chan Bang

Yeon Im Lee

Hee Kyoon Yoon

Yun Soo Na

Yong Lee Bong

Yeon Jung Park

Wol Young Kim

Jaehyun Jung

An intermediate useful for the synthesis of an SGLT inhibitor and a method for preparing an SGLT inhibitor are provided. By employing an intermediate having Chemical Formula 5, the difficulty of purification with existing processes can be solved, the quality requirements for related substances can be achieved with only one purification step, and the quality control problem in each step can be solved by performing several steps in situ. A method for synthesizing a compound of Chemical Formula 1 by using a compound of Chemical Formula 5 enables purification in an earlier step, thereby solving the problems of existing synthesis processes, in which the quality requirements for related substances were difficult to control step-by-step due to a continuous process, thereby minimizing the amount of related substances in the final product. In addition, the yield of a diphenylmethane derivative according to Chemical Formula 1 is increased.

Intermediate useful for synthesis of SGLT inhibitor and method for preparing SGLT inhibitor using same

The present disclosure relates to a novel heterocyclic amine derivative represented by the following Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers.

Heterocyclic amine derivative and pharmaceutical composition comprising same

The present invention relates to a compound represented by chemical formula 1, which can be used for the prevention and treatment of diseases caused by abnormality in a prolyl-tRNA synthetase (PRS) activity, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition comprising the same.

Heterocyclic compound

The present invention relates to a heterocyclic compound having a novel structure that can be used in the prevention or treatment of diseases caused by abnormality in a PRS (prolyl-tRNA synthetase) activity, a method for preparing the same, and a pharmaceutical composition comprising the same.

Heterocyclic compound, method for preparing the same, and pharmaceutical composition comprising the same

The present invention relates to novel oxodihydropyridinecarbohydrazide derivatives with excellent antifungal activities, an antifungal composition containing the same, and its use for the prevention and treatment of fungal infectious diseases. The oxodihydropyridinecarbohydrazide derivatives of the present invention have excellent antifungal and fungicidal activities, and thus will be useful for the prevention and treatment of various fungal infections byspp.,spp.,andspp., etc. Additionally, the oxodihydropyridinecarbohydrazide derivatives of the present invention, unlike other fungicidal preparations, can be orally administered.

Antifungal oxodihydropyridinecarbohydrazide derivative

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Gyeonggi-do, South Korea

Youn Jung Yoon