Posco

Postech Academy-industry Foundation

Pohang University of Science and Technology Foundation

Youn-Dong Kim

Sung-Ho Ryu

Pann-Ghill Suh

Jung-Hwan Lee

Yoe-Sik Bae

Jong-In Kim

Sung-Key Jang

Jong-Hun Im

Young-Chan Chae

Ki-Seok Kim

Mi-Jin Kwon

Hyun-Gu Kang

Taehoon Lee

Tae-Hoon Lee

Hye-Jung Lee

Eun-Jung Jang

Sun-Hak Lee

Hyunjoo Bae

Dong-II Han

Bum-Su Park

Seung-Jin Lee

You-Suk Seo

Young-Chul Sung

Soon-Hag Kim

The present invention provides methods for identifying the plurality of aptamers that bind to different sites of a target molecule and methods for using the same, for example, in sandwich assays. In particular, the plurality of aptamers binding to different sites of the target molecules is identified from a library of aptamers identified from the same SELEX process.

Aptamer sandwich assays

Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.

Nucleolin specific aptamer and use thereof

Disclosed are peptides having SEQ ID NOs: 1 to 32 that can stimulate superoxide generation in human monocytes. Superoxide is the most important armory on the primary defense line of monocytes against invading pathogens, and the identification of new stimuli and the characterization of the regulatory mechanism of superoxide generation are of paramount importance.

Immune-enhancing peptides

A vaccine having a good vaccination effect, which comprises an antigen; a peptide selected from the group consisting of a peptide having the amino acid sequence of SEQ ID NO: 1, a peptide having the amino acid sequence of SEQ ID NO: 2, and a peptide derived from a peptide having the amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 2; and an immune activator.

Vaccine composition containing a promoter peptide

Growing community of inventors

Pohang-si, South Korea

Youn-Dong Kim