Ajinomoto Co., Ltd.

Youji Yamada

Shinichi Fujita

Tamotsu Suzuki

Tatsuya Okuzumi

Tadakiyo Nakagawa

Yoichiro Shima

Masahiro Murata

Toshihiko Yoshimura

Tetsuo Yano

Kaoru Takenaka

Masanao Yoshida

Hideki Matsumoto

Naoyuki Fukuchi

Munetaka Tokumasu

Shingo Makino

Sayaka Asari

Masataka Shoji

Itsuya Tanabe

Masaki Hashimoto

Yoriko Yamamoto

Amide derivatives represented by the formula (I): wherein:

Amide derivative

The present invention relates to an ether derivative represented by the formula (I), a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof wherein each symbol is as defined in the description, and an ether derivative represented by the formula (III), a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof wherein each symbol is as defined in the description; a pharmaceutical composition containing the ether derivative; and a package containing the pharmaceutical composition and a description of use thereof. A pharmaceutical composition of the present invention, which contains this compound of the present invention has a superior anti-inflammatory and analgesic activity and is useful as various pharmaceutical agents such as an anti-inflammatory agent, an analgesic, a therapeutic agent for inflammatory bowel disease, a therapeutic agent for pollakiuria and/or incontinentia, a therapeutic agent for asthma and the like.

Ether derivative

The present invention provides a piperidine derivative represented by the following formula or analogs thereto, which are used for agents for treating or preventing various diseases related to 5-HT7. 

Piperidine derivative

Growing community of inventors

Kawasaki, Japan

Youji Yamada