Korea Advanced Institute of Science and Technology

Korea Institute of Science and Technology

Amorepacific Corporation

You Seung Kim

Sang Woo Park

Jea Cheol Kim

Ju Ho Kim

Ae Nim Pae

Yong Seo Cho

Hyunah Choo

Sung Soo Hong

Soon Bang Kang

Jae Kyun Lee

Seon Hee Park

The present invention relates to a cosmetic container comprising a refill container having a sealing ring and, more specifically, to a cosmetic container comprising a refill container having a sealing ring, the cosmetic container having a refill container holder embedded in an outer case, and having the refill container, which contains cosmetics, used by being coupled to the refill container holder, and improving refill convenience since after the cosmetics are completely used, a user easily separates the refill container from the refill container holder by pressing the refill container on the top thereof, and then can couple a new refill container to the refill container holder from the bottom of the outer case, thereby easily replacing the refill container.

Cosmetic container comprising refill container having sealing ring

Disclosed are cis-2,6-disubstituted tetrahydropyran derivatives represented by Chemical Formula 1 and a preparation method thereof. The tetrahydropyran derivatives can be prepared by Prins-reacting tetrahydropyran derivatives with homopargylicalcohol derivatives in the presence of trimethylsilyltriflate. The tetrahydropyran derivatives with cis-substituents at both C2 and C6 positions of the tetrahydropyran ring are useful as intermediates for use in the synthesis and development of therapeutically effective, naturally occurring compounds.  (wherein, R, Rand Rare as defined in the specification.).

Cis-2, 6-disubstituted tetrahydropyran derivatives and preparation method thereof

2-benzoyl-3-aminoacrylate derivatives of the following formula I and methods for the preparation of the same. ##STR1## wherein X is a halogen; X.sub.1 and X.sub.2 are independently selected from a halogen and a nitro; and R, R.sub.1 and R.sub.2 each is an alkyl group containing 1 to 4 carbon atoms. The compounds can be used as starting materials to synthesize benzoxazine derivatives, potent antibacterial compounds.

2-benzoyl-3-aminoacrylate derivatives and methods for the preparation of

Nitrobenzoyl-3-cyclopropylaminoacrylates are prepared by two stage reaction: a) The first stage is the synthesis of nitrobenzoyl-3-alkoxyacrylates from nitrobenzoylester compound and alkylorthoformate in organic acid solvent. b) The second stage is the synthesis of nitrobenzoyl-3-cyclo propylamino acrylate from nitrobenzoyl-3-alkoxyacrylates and cyclopropylamine.

Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the

Nitrobenzoyl-3-cyclopropylaminoacrylates are prepared by two stage reaction: (a) The first stage is the synthesis of nitrobenzoyl-3-alkoxyacrylates from nitrobenzoylester compound and alkylorthoformate in organic acid solvent. (b) The second stage is the synthesis of nitrobenzoyl-3-cyclo propylamino acrylate from nitrobenzoyl-3-alkoxyacrylates and cyclopropylamine.

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Seoul, South Korea

You Seung Kim