Jeju National University Industry-Academic Cooperation Foundation

Gachon University of Industry-Academic Cooperation Foundation

You-Jin Jeon

Yung Hyun Choi

Bae Jin Lee

Areum Kim

BoMi Ryu

Jae-Young Oh

Ji-Yeon Chun

Gi-Young Kim

Hyo-Jin Kim

Young-Heun Jee

Eui Kyun Park

Hyun-Jung Kim

Hye Sun Lee

Seyeon Oh

Myeongjoo Son

Kyunghee Byun

Junwon Choi

Bomi Ryu

Disclosed is a pharmaceutical composition or food composition for the treatment or prevention of hypertension, containing a peptide isolated from a fraction of a flounder surimi hydrolysate as an active ingredient and is based on the finding that the flounder surimi has an effect of reducing blood pressure, and the hydrolysate of the flounder surimi, the fraction of the hydrolysate of the flounder surimi and peptides isolated from the fraction of the hydrolysate of the flounder surimi have an inhibition activity against an angiotensin I converting enzyme (ACE). Thus, peptides isolated from the fraction of the hydrolysate of the flounder surimi can be used for pharmaceutical compositions or food compositions for treating or preventing hypertension. Also, the present invention is based on the finding that the hydrolysate of the flounder surimi and peptides isolated therefrom have radical scavenging effect and a protective effect against oxidative stress and are thus capable of inhibiting ROS production, lipid peroxidation and apoptosis. Accordingly, peptides isolated from fractions of the hydrolysate of the flounder surimi can be used for food compositions for antioxidation.

Flounder surimi having antioxidant and antihypertensive effects and method of preparing the same

The present invention relates to a composition for improving bone health, and the composition includes a fermented extract extracted from a fermented material of oysters, which is obtained by fermenting oysters, and the fermented extract may promote bone formation by suppressing the activity of osteoclasts and promoting the activity of osteoblasts. The composition contains large amounts of taurine and vitamins, and natural gamma-aminobutyric acid.

Composition for promotng bone formation with fermented oysters and seaweed

Disclosed herein are hexadecaphlorethol (HdP), which is a novel compound isolated from, and the use thereof in anti-diabetic treatment and exercise performance improvement. The novel compound HdP has the activity of inhibiting &#x3b1;-glucosidase, inducing glucose uptake into differentiated myoblast C2C12 cells, reducing blood glucose levels in zebrafish which have reduced insulin secretion through treatment with alloxan, increasing an intracellular level of calcium ions necessary for muscle contraction and exercise performance in zebrafish, and inducing uptake of glucose, an energy source necessary for muscle contraction, into cells.

Compound hexadecaphlorethol isolated fromand use thereof

Disclosed is a composition comprising aextract for alleviating lung injury or respiratory disease.

Composition comprisingextract for alleviating lung injury or respiratory disease

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Jeju-si, South Korea

You-Jin Jeon