International Business Machines Corporation

Chinese Academy of Sciences

Lianhe Chemical Technology Co., Ltd

Lianhe Chemical Technology (taizhou) Co., Ltd

You Hang Wang

Wen Bao Yin

Dawei Ma

Shaolin Zhu

Shouyun Yu

Xu Yue

Qianghui Zhou

Method and apparatus for global routing optimization are provided herein. Optimizing global routing of a circuit, includes recursively generating, in parallel, a plurality of candidate wiring layouts for an integrated circuit, wherein each candidate wiring layout of the plurality of candidate wiring layouts corresponds to a respective parameter super-group of a plurality of parameter super-groups, wherein the plurality of parameter super-groups form a parameter set; calculating a Quality of Result (QoR) measure for each candidate wiring layout in an iteration; combining selected parameter super-groups of the iteration, based on the QoR measure, to form a new plurality of parameter super-groups for a next iteration; and determining a best parameter super-group from the parameter sets for use in globally routing the circuit.

Global routing optimization

Chiral amino compounds, methods of preparation and uses thereof. Tamiflu can be obtained from the said compounds. Multi-substituted chiral tetrahydropyrrolyl amine which can be used as intermediate compounds of medicament can also be produced by the said compounds.

Intermediate compounds of tamiflu, methods of preparation and uses thereof

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Shanghai, China

You Hang Wang