Nano-retina, Inc.

Biocontrol Medical Ltd.

Brainsgate Ltd.

Glusense Ltd.

Yossi Gross

Yaakov Milstain

David Rigler

Dorit Raz Prag

Rani Mendelewicz

Ehud Cohen

Boris Degtiar

Matan Zehavi

Alon Shalev

Israel Nissenkorn

David Lifschitz

Boaz Hyman

Dov Weinberger

Tehila Hyman

Orly Grinberg

Itamar Weisman

A ventricular assist device (VAD) for use with a heart includes a housing, an upper membrane pump including a pumping chamber coupled to one-way upper inlet and outlet valves, a lower membrane pump including a pumping chamber coupled to one-way lower inlet and outlet valves, and an actuator that causes the upper membrane pump and the lower membrane pump to alternately draw blood into and pump blood out of their respective pumping chambers, and a control module in operative communication with the actuator, wherein the actuator operates with a pumping frequency which is greater than a pulse frequency of the heart.

Ventricular assist device

Apparatus is provided that includes a retinal stimulator, which includes an electrode array including electrodes, which are configured to be coupled to a retina of a subject's eye; and driving circuitry, configured to drive the electrodes to apply currents to the retina. The retinal stimulator further includes an elastic anchor that is coupled to the retinal stimulator and is configured to anchor the electrodes to the retina without the elastic anchor penetrating the retina. Other embodiments are also described.

Retinal implant fixation

Apparatus is provided including an implantable retinal stimulator, for implantation on a retina of an eye, and including (i) an electrode array including electrodes; (ii) a plurality of photosensors; and (iii) driving circuitry, configured to drive the electrodes to apply currents to the retina. The apparatus further includes an interface member disposed at an outer surface of the implantable retinal stimulator, e.g., a peripheral member surrounding at least a portion of the implantable retinal stimulator. The apparatus additionally includes a frame, (i) shaped and sized to couple to the peripheral member and to surround the implantable retinal stimulator at least in part, and (ii) shaped to define at least a first anchoring element receiving portion. An anchoring element is shaped and sized to be positioned in the anchoring element receiving portion and to penetrate scleral tissue of the subject. Other applications are also described.

A method is provided for implanting, in an eye, apparatus having an electrode array including stimulating electrodes shaped to define distal tips protruding from the array, a plurality of photosensors, and driving circuitry, configured to drive the electrodes to apply currents to the retina. The method includes removing a lens of the eye and a vitreous body of the eye, creating a corneoscleral incision and inserting the apparatus through the corneoscleral incision into a vitreous cavity of the eye. During the inserting, an orientation of the distal tips is maintained pointing towards a cornea of the eye. Subsequently to the inserting, the apparatus is rotated such that the distal tips point towards a macula of the eye. Subsequently to the rotating, the apparatus is positioned epi-retinally, such that the distal tips of the electrodes penetrate the retina. Other applications are also described.

Surgical techniques for implantation of a retinal implant

Apparatus is provided for detecting an analyte, configured to be implanted in a body of a subject. The apparatus includes an optical fiber having a distal portion and also a membrane permeable to the analyte. The membrane is coupled to the distal portion of the fiber and surrounding a sampling region at least in part, by being fitted over the distal portion of the fiber. Other embodiments are also described.

Implantable optical glucose sensing

Apparatus for actuating a skeletal muscle of a patient is provided. The apparatus typically includes a plurality of electrodes, which are adapted to be placed in a vicinity of a motor nerve that innervates the skeletal muscle. A control unit, is preferably adapted to drive a current between two or more of the plurality of electrodes, and to configure the current such that a first subset of axons in the nerve is excited by the current and such that a second subset of axons in the nerve is not excited by the current.

Actuation and control of limbs through motor nerve stimulation

Apparatus for modifying a property of a brain of a patient is provided, including one or more electrodes (), adapted to be applied to a site selected from a group of sites consisting of: a sphenopalatine ganglion (SPG) () of the patient and a neural tract originating in or leading to the SPG. A control unit () is adapted to drive the one or more electrodes to apply a current to the site capable of inducing (a) an increase in permeability of a blood-brain barrier (BBB) of the patient, (b) a change in cerebral blood flow of the patient, and/or (c) an inhibition of parasympathetic activity of the SPG.

Method and apparatus for stimulating the sphenopalatine ganglion to modify properties of the BBB and cerebral blood flow

A device ( ) for treatment of a patient's urinary incontinence, including a sensor ( ), which generates a signal responsive to a physiological characteristic indicative of a likelihood of incontinence. A control unit ( ) receives the signal from the sensor. At least one electrode ( ) is preferably implanted in the patient. The electrode is coupled to cause contraction of the pelvic muscle of the patient responsive to application of electrical energy to the electrode. Responsive to the signal, the control unit applies an electrical waveform to the electrode, so as to inhibit the incontinence.

Growing community of inventors

Mazor, Israel

Yossi Gross