Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

Hadasit Medical Research Services and Development Ltd.

Aristotle University of Thessaloniki

Yossi Dagon

Yosefa Avraham

Elliot Berry

Yaron Ilan

Raphael Mechoulam

Iddo Magen

Nicholas Grigoriadis

Theofilos Poutachidis

The compounds D9-tetrahydrocannabinol (THC), cannabidiol (CBD) and capsaicin are useful for prevention, treatment, or both, of hepatic encephalopathy. The compounds capsaicin, 2-arachidonoylglycerol (2-AG), HU-308 and cannabidiol are useful for prevention, treatment, or both, of liver cirrhosis.

Treatment of hepatic encephalopathy and liver cirrhosis

The present invention concerns using a leptin protein, a variant fragment or mimic of a leptin protein, or an activator of the AMPK signal transduction pathway for preparing a medicament that can either be used to improve cognitive function or to treat treatment of undesirable manifestations of a nutritional stress condition and to prolong survival.

Compounds for improving nutritional status, cognition and survival

Growing community of inventors

Ness Ziona, Israel

Yossi Dagon