Hitachi, Ltd.

Hitachi-High-Technologies Corporation

Yoshiyuki Okishima

Masaya Kojima

Tomohiro Shoji

Tomonari Morioka

Ryoji Inaba

Yasushi Shimizu

Takayasu Furukawa

Akihiro Suzuki

Shuhei Yamamoto

Muneo Maeshima

Seiichi Ugai

Toshiaki Kita

Masao Fukunaga

Daizo Tokinaga

Kiyoshi Tsukada

Hiroyuki Tanaka

Noriyuki Shimoda

Syouzou Kasai

Wataru Matsuo

Motohiro Yamazaki

Takashi Gomi

Yoshinori Ookoshi

Tsukasa Ohira

Tomihiro Shoji

A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.

Capillary array

At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.

Capillary array electrophoresis apparatus and method of separating and analyzing specimen

In a case where the temperature of capillaries cannot be controlled rapidly in accordance with the change of the amount of heat generated from the capillaries, the phoretic speed of the sample is not controlled constant to lower the analyzing performance for the sample. This invention intends to stabilize the electrophoretic speed. The surface of a substrate on which a plurality of capillaries are arranged is in contact with a member capable of temperature control thereby controlling the temperature of the capillaries. Since a member capable of controlling the temperature and the capillaries are in direct contact with each other according to the invention, the temperature of the capillary can be controlled rapidly at a high accuracy, so that electrophoretic speed is stabilized.

Capillary array and capillary electrophoresis apparatus

The capillary electrophoresis device using one pressure-resistant syringe () is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (). An electric hook () is installed for pulling up the syringe plunger on a push-in action type syringe (). A check valve () is inserted between a polymer bottle () and syringe to prevent solution from flowing back into the polymer bottle. As a result, one syringe portion of polymer solution can be suctioned and injected, a large volume of polymer solution can be continuously used and device processing capability is improved.

Capillary electrophoresis device

The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes. According to the present invention, a connection plateand hollow electrodesare connected without solder but via a spring force. Alternatively, the hollow electrodescan be connected to the connection plateby utilizing volume elasticity of the connection plate.

Capillary array device

An injection syringe 14 for injecting a gel into a capillary 111, a charging syringe 15 for charging the injection syringe 14 with the gel 10 are attached to a block 17. A check valve 16 is inserted between the both syringes, and the check valve 16 works so as to prevent the gel 10 from flowing back to the charging syringe 15. As the result, the gel charging can be automated, and accordingly the processing ability of the electrophoretic instrument can be improved.

Electrophoretic method and electrophoretic instrument therefor

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Minori, Japan

Yoshiyuki Okishima