Biomaterials Universe, Inc.

Gunze Limited

Dow Corning Corporation

Toyo Jozo Company, Ltd.

Japan Medical Supply Co., Ltd.

Sanraku Incorporated

Gunze Co., Ltd.

Bio-materials Universe Company

Yamada, Shiro

Ikada, Yoshito

Yoshito Ikada

Suong-Hyu Hyon

Shokyu Gen

Yuki Sakamoto

Shojiro Matsuda

Goki Matsumura

Daniel Graiver

Shiro Yamada

Tatsuya Kawai

Tsuguyoshi Taira

Hiroshi Yoshikawa

Toshiharu Shinoka

Kenji Tomihata

Shigehiko Suzuki

Yoshitake Takahashi

Shozo Muranishi

Fumihiro Ishimura

Sho-kyu Gen

Koji Murata

The present invention aims to provide a material for revascularization which enables the regeneration of a blood vessel at an extremely high efficiency by being transplanted into a defect of the blood vessel. The present invention provides a tubular material for revascularization comprising a foamed body comprising a bioabsorbable material, a reinforcing member comprising a bioabsorbable material for reinforcing the foamed body, and a reinforcing yarn comprising a bioabsorbable material for reinforcing the foamed body, wherein the reinforcing yarn and the reinforcing member are located at the center or outer face of the foamed body, the inner face thereof is the foamed body, the reinforcing yarn is wound around in a spiral-shaped, ring-shaped or X-shaped manner, and the reinforcing yarn comprises a glycolide-&#x3b5;-caprolactone copolymer.

Base material for revascularization

The scaffold for culturing a cardiovascular tissue of the present invention is a scaffold for culturing a cardiovascular tissue, which is tubular, and comprises a foamed polymer comprising a bioabsorbable material reinforced with a reinforcing material comprising a bioabsorbable material, the foamed polymer comprising lactide (D, L, DL isomer)-&#x3b5;-caprolactone copolymer containing lactide (D, L, DL isomer) in a content of 50 to 54 mole % and &#x3b5;-caprolactone in a content of 50 to 46 mole %, and the reinforcing material being covered with the foamed polymer.

Substrate for culture of cardiovascular tissue

A process is provided for the preparation of expanding-contracting hydrogel composites which process comprises the steps of adding solid particles of a polyelectrolyte to a polyvinyl alcohol solution and subjecting the mixture to a low temperature treatment to cause gelation of the polyvinyl alcohol with the polyelectrolyte dispersed as a heterogeneous phase (i.e. solid particles) within the polyvinyl alcohol gel. Hydrogel composites made by the process exhibit high strength and a capacity to expand and contract over a wide range with changes in environment.

Expanding-contracting hydrogel composite and process for preparation

Polylactic acid microspheres having an average particle diameter of about 0.1 to 10 .mu.m which are produced from solution containing a physiologically active substance by the solvent-evaporation drying process. The microspheres are produced by emulsifying the solution in a non-solvent by the aid of ultrasonic wave. The microspheres produce a sustained release effect of the physiologically active substance.

Polylactic acid microspheres and process for producing the same

A suture coating composition comprising a sucrose fatty acid ester and sutures coated therewith whereby said sutures exhibit improved smoothness in tie-down properties and knotting can be readily accomplished using said suture.

Sucrose fatty acid ester coated suture

A porous gel containing an immobilized enzyme is prepared by mixing an aqueous solution of polyvinyl alcohol having a saponification degree of not lower than 95 mol% and an average polymerization degree of not lower than 1,000, with an enzyme or enzyme-producing cell, and activated carbon powder, pouring the mixture into a container of any desired form, gelating and molding the mixture by dehydrating it up to a dehydration ratio of not lower than 50%, immersing the resulting molding in water, and drying the immersed molding. Preferably, dehydrating is by leaving the mixture to stand at room temperature or a temperature of from 30.degree. C. to 40.degree. C. The enzyme or enzyme-producing cell may be mixed with or adsorbed on an inorganic or organic carrier. The dried molding may be granulated.

Preparation of porous polyvinyl alcohol gel containing an immobilized

A porous and transparent hydrated gel is prepared from a poly(vinyl alcohol) solution in a mixed solvent consisting of water and an water-miscible organic solvent. Upon cooling the poly(vinyl alcohol) solution below room temperature, a gel is formed as a consequence of crystallization of poly(vinyl alcohol) molecules. Exchange of the organic solvent included in the gel with water produces a hydrated gel of poly(vinyl alcohol) which has a high tensile strength, a high water content, and a high light transmittance.

Porous and transparent poly(vinyl alcohol) gel and method of

Growing community of inventors

Kyoto, Japan

Yoshito Ikada