Wakamoto Pharmaceutical Co., Ltd.

Yoshitami Ohashi

Nobuyuki Suzuki

Makoto Maeda

Masayoshi Goto

Haruhisa Hirata

Hirokazu Suzuki

Seigo Nakaya

Yuji Aiba

Azusa Katou

Naomi Kokubo

Yoshinori Sakurai

Antibiotics WAP-8294A, A.sub.1, A.sub.2, A.sub.4, AX, AX-8, AX-9 and AX-13 or pharmeceutically acceptable salts thereof produced by a strain belonging to the genus Lysobacter; a method for producing the foregoing antibiotic WAP-8294A comprising the steps of cultivating, in the culture medium, a microorganism belonging to the genus Lysobacter and having an ability of producing the antibiotic WAP-8294A to produce the antibiotic and accumulate it in the culture medium; then recovering the antibiotic; as well as an antibacterial composition comprising the antibiotic or pharmaceutically acceptable salts thereof are herein disclosed. The novel antibiotic WAP-8294A has an excellent therapeutic effect on infectious diseases developed by infection with Gram-positive bacteria, in particular, MRSA and, therefore, the antibiotic is effective for treating diseases including MRSA infectious diseases developed through infection with Gram-positive bacteria as infectious bacteria.

Antibiotic WAP-8294A, method for preparing the same and antibacterial

A method of diagnosing renal diseases by detecting fragments of albumin in human urine. The detection of the fragments is carried out by, for example, immunological methods or liquid chromatography techniques.

Method of diagnosing renal diseases

Growing community of inventors

Hatano, Japan

Yoshitami Ohashi