Meito Sangyo Kabushiki Kaisha

Meito Sangyo Co., Ltd.

Kao Corporation

Yoshitaka Kokusho

Haruo Machida

Shigeaki Kato

Shinjiro Iwasaki

Akira Tsunoda

Tomihiro Kurosaki

Takashi Imamura

Katsumi Kita

Yasuo Ishii

Mitsuharu Masuda

Haruya Kato

Akio Oshima

Yoshiko Chikawa

Takashi Itoh

Noriko Inoue

Susumu Higashi

Disclosed is a process for the interesterification of oil or fat by treating such oil or fat in presence of a fatty acid or fatty acid ester or different oil or fat wherein a reactor column that is packed with an alkaline high molecular weight lipase preparation containing 0 to 5% moisture is fed with a substrate solution composed of the above oil or fat and fatty acid or fatty acid ester or different oil or fat for a continuous reaction in such a manner that the substrate solution contains 100 to 1800 ppm moisture and 50 to 800 ppm moisture at the inlet and outlet, respectively, of the column.

Continuous process for the interesterification of fats or oils

A novel monophosphate and a novel diphosphate prepared by a phosphatidyl transfer reaction of a phospholipid and an alcohol in the presence of phospholipase D are disclosed. The phosphates can independently or together form small and stable liposomes which can include active components therein. Cosmetic compositions comprising these phosphates or liposomes penetrate well into the hair and the skin, and exhibit long-lasting excellent moisture-retaining, beauty, skin-activation effects.

Phosphate, liposome comprising the phosphate as membrane constituent,

A process for producing a primary or secondary alcohol derivative of a phosopholipid which comprises reacting the phospholipid with a primary or secondary alcohol in the presence of phospholipase DM.

Production of primary or secondary alcohol derivatives of phospholipids

A process for producing a sphingophospholipid derivative comprising reacting a sphingophospholipid with a specified compound having an alcoholic hydroxyl group selected from the group consisting of specified primary alcohol compounds, specified secondary alcohol compounds and specified saccharides or their phenol glycosides in the presence of phospholipase DM.

Enzymatic production of sphingophospholipid derivatives

A process for producing a saccharide derivative of a phospholipid, which comprises reacting a phospholipid with a monosaccharide having 5 to 7 carbon atoms, at least one primary alcohol group and at least three hydroxyl groups in total including the OH of the primary alcohol group or a disaccharide thereof, said saccharide being optionally substituted by a group selected from the class consisting of amino and acetylamino groups, or a phenol glycoside of said saccharide in the presence of phospholipase DM. The phospholipid-saccharide derivatives are useful as a liposome-forming substrate, or as an emulsifier for cosmetics, such as cream and lotion, fat solutions for transfusion and agricultural chemicals, such as pesticides and herbicides.

Enzymatic production of phospholipid-saccharide derivatives

A microbial lipase which has (i) an optimal pH for activity of about 9.+-.0.5, (ii) an optimal temperature for activity of about 40.degree. C. to about 48.degree. C., (iii) a lipase activity to be activated by bile salts, (iv) a cholesterol esterase activity, and (v) a molecular weight of about 30.times.10.sup.4 to about 40.times.10.sup.4 ; a process for its preparation; and microbiologically pure culture therefor.

Microbial lipase, process for its preparation and microbiologically pure

A process for improving the quality of microbial rennet by inactivating cellulase impurities in microbial rennet which comprises heat-treating microbial rennet in an aqueous medium in the presence of sodium chloride.

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Kunitachi, Japan

Yoshitaka Kokusho