Mitsubishi Petrochemical Company Limited

Mitsubishi Yuka Pharmaceutical Co., Ltd.

Yoshiro Masuda

Toshiji Kanayama

Motokuni Mori

Tsuneo Nozawa

Fujio Endo

Yoshihiro Takayama

Naoto Miwa

Toshiyuki Sai

Seiichi Kawarabuki

Toshihiro Takayama

Takao Saito

New polysaccharide named M-30-C produced by cultivation of new strain Pseudomonas polysaccharogenes M-30 and having utility as hypocholesterol agents.

Novel polysaccharide and hypocholesterol composition containing the same

This invention relates to a process for producing collagenase, which comprises aerobically cultivating a collagenase-producing bacterium belonging to the genus Bacillus, and recovering collagenase from the culture broth. This invention also provides a thermophilic bacterium of the genus Bacillus which has the ability to produce collagenase and which grows at a temperature of 42.degree. to 74.degree. C. and a pH of 5.0 to 9.0 and a novel thermophilic collagenase which does not substantially lose collagenase activity even when maintained for 1 hour at a temperature of 60.degree. C. in the presence of a calcium ion at a pH in the range of 6.5 to 8.5, and which has a molecular weight, determined by gel filtration, between those of cytochrome C and ovalbumin.

Thermophilic collagenases, thermophilic bacteria capable of producing

Process for producing a polysaccharide using Pseudomonas

Growing community of inventors

Ami, Japan

Yoshiro Masuda