Takeda Pharmaceutical Company Limited

National Institute of Advanced Industrial Science and Technology

Yoshio Matsumoto

Takuya Watanabe

Chieko Kitada

Masaaki Mori

Taiji Asami

Yukio Shimomura

Tsukasa Sugo

Mika Goto

Mioko Harada

Yuka Adachi

Michiko Abe

Hideyuki Tanaka

Yasushi Sumi

A pose detecting system includes: a marker using a microlens array; a camera; and a computer receiving a marker image. The marker includes: a lens area constituted of the microlens array and a mark array having a plurality of marks arrayed with a pitch similar to that between a plurality of lenses constituting the microlens array so as to produce a moir&#xe9; pattern; and four reference points. The computer performs: determining the pose of the marker based on the four reference points; analyzing the moir&#xe9; pattern so as to calculate an angle formed by the marker and a straight line connecting the center of an integrated mark that emerges at the lens area as the moir&#xe9; pattern and is similar in shape to each of the plurality of marks to a viewpoint at the marker; and correcting the pose of the marker by using the angle.

Method and system for detecting pose of marker

The present invention provides a ligand to GPR8, in particular polypeptides capable of binding to GPR8 or its amides or esters, or salts thereof, as well as the DNA encoding for such polypeptides. The ligand to GPR8 of the present invention is useful in developing receptor-binding assay systems with the use of a GPR8 expression system, for screening candidate compounds for drugs such as preventive/therapeutic agents for obesity, appetite stimulants, and prolactin production inhibitors.

Ligand to GPR8

The present invention provides a ligand to GPR8, in particular polypeptides capable of binding to GPR8 or its amides or esters, or salts thereof, as well as DNA, encoding for such polypeptides. The ligand to GPR8 of the present invention is useful in developing a receptor-binding assay system with the use of a GPR8 expression system, for screening candidate compounds for drugs such as preventive/therapeutic agents for obesity, appetite stimulants, and prolactin production inhibitors.

Peptide having appetite stimulating activity

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Tsukuba, Japan

Yoshio Matsumoto