Other

Takeda Chemical Industries, Inc.

Yoshio Hayashi

Hiromu Sugino

Screening of the autoantibodies and autoantigens which are specific to Sj&ouml;gren's syndrome, particularly primary Sj&ouml;gren's syndrome, and provision of a prophylactic and therapeutic drug for Sj&ouml;gren's syndrome, particularly primary Sj&ouml;gren's syndrome, and a highly sensitive diagnostic agent for Sj&ouml;gren's syndrome. The &agr;-fodrin or &agr;-fodrin fragment of the invention is an antigen to the autoantibodies specifically found in Sj&ouml;gren's syndrome and this autoantigen finds application as a prophylactic and therapeutic drug for autoimmune diseases, particularly Sj&ouml;gren's syndrome, or a diagnostic agent for such diseases.

Composition containing &agr;-fodrin or &agr;-fodrin fragment protein

Screening of the autoantibodies and autoantigens which are specific to Sjogren's syndrome, particularly primary Sjogren's syndrome, and provision of a prophylactic and therapeutic drug for Sjogren's syndrome, particularly primary Sjogren's syndrome, and a highly sensitive diagnostic agent for Sjogren's syndrome. The .alpha.-fodrin or .alpha.-fodrin fragment of the invention is an antigen to the autoantibodies specifically found in Sjogren's syndrome and this autoantigen finds application as a prophylactic and therapeutic drug for autoimmune diseases, particularly Sjogren's syndrome, or a diagnostic agent for such diseases.

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Tokushima-shi, undefined

Yoshio Hayashi