Calpis Co., Ltd.

Genomembrane, Inc.

Okayama University

Yoshinori Moriyama

Hiroshi Omote

Toshiaki Takano

Akihiro Masuyama

Masato Otsuka

Takuya Matsumoto

Miki Hiasa

Seiji Tsuboi

Teppei Nakamura

Keita Ueno

Toshiyuki Kai

Keisuke Sawada

The present invention provides a lipid membrane that contains a polypeptide consisting of the amino acid sequence of SEQ ID NO: 2, 4, 6, 8, or 22. Use of the present invention enables screening for a chemical which regulates excretion of a chemical and/or a waste. Furthermore, use of the present invention enables an arbitrary chemical to be tested for nephrotoxicity and/or hepatotoxicity.

Transporter protein in mammal and utilization of the same

Disclosed are agents for phase-adjusting or enhancing the amplitude of an endogenous melatonin secretion rhythm and for improving a circadian rhythm, as well as functional food containing such an agent, which may prevent or ameliorate various symptoms, such as sleep disorder or prolonged sleep latency. The agent contains whey as the active component.

Functional food for ameliorating endogenous melatonin secretion rhythm and functional food for ameliorating circadian rhythm

It is an object of the invention to isolate a transporter responsible for ATP transport and a gene encoding the transporter. It is another object of the invention to provide a method for the screening of a medicament for treating and/or regulating pain in central nerves, blood coagulation by platelet-derived ATP, or the like, the method employing such a transporter. According to the invention, a transporter responsible for ATP transport and a gene encoding the transporter were isolated. Furthermore, there is provided a method for the screening of a medicament for treating and/or regulating pain in central nerves, blood coagulation by platelet-derived ATP, or the like, the method employing such a transporter.

Methods for screening modulators of SLC17-type anion transport activity

The present invention provides an agent for preventing or suppressing hepatic dysfunction which may be taken daily and continuously, has excellent safety, and is capable of effectively preventing and/or suppressing hepatic dysfunction, such as hepatocellular necrosis, and functional food, such as foods for specified health uses, for preventing or suppressing hepatic dysfunction containing this agent. The agent for preventing or suppressing hepatic dysfunction of the present invention contains whey as the active component, and the functional food for preventing or suppressing hepatic dysfunction contains the agent for preventing or suppressing hepatic dysfunction.

Agent for preventing or suppressing hepatopathy and functional food for preventing or suppressing hepatopathy

Growing community of inventors

Okayama, Japan

Yoshinori Moriyama