Panasonic Corporation

Matsushita Electric Industrial Co., Ltd.

Other

Arkray, Inc.

Phc Holdings Corporation

Panasonic Healthcare Holdings Co., Ltd.

Panasonic Healthcare Co., Ltd.

Yoshinobu Tokuno

Shoji Miyazaki

Hiroyuki Tokunaga

Masaki Fujiwara

Shinichi Kojima

Eriko Yamanishi

Toshihiko Yoshioka

Shiro Nankai

Shin Ikeda

Hideyuki Baba

Haruhiro Tsutsumi

Shoji Kawanaka

Yoshiharu Sato

Kazuhiro Matsumoto

Kohei Ishida

Yasuhiko Sawada

Syoji Miyazaki

Yoshinori Amano

Junji Nakatsuka

Yuko Taniike

Mariko Kawaguri

Mariko Miyashita

Masufumi Koike

Hiroya Ueno

Yoshihiro Kataoka

Yasuhito Kawamata

Tadayoshi Ishikawa

A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes, and a driving power terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

Biosensor, measuring instrument for biosensor, and method of quantifying substrate

A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltages to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

A biosensor is disclosed comprising a support; a conductive layer composed of an electrical conductive material such as a noble metal, for example gold or palladium, and carbon; slits parallel to and perpendicular to the side of the support; working, counter, and detecting electrodes; a spacer which covers the working, counter, and detecting electrodes on the support; a rectangular cutout in the spacer forming a specimen supply path; an inlet to the specimen supply path; a reagent layer formed by applying a reagent containing an enzyme to the working, counter, and detecting electrodes, which are exposed through the cutout in the spacer; and a cover over the spacer. The biosensor can be formed by a simple method, and provides a uniform reagent layer on the electrodes regardless of the reagent composition.

Biosensor, thin film electrode forming method, quantification apparatus, and quantification method

A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

Method of measuring quantity of substrate

A sensor and a lancet are integrated with each other. A thin strip-shaped sensor and a lancet are integrated so that the lancet moves in parallel, along a longitudinal direction of the sensor. A measuring device to which an integrated lancet and sensor is attached is provided with a function of driving the attached lancet.

Lancet-integrated sensor, measuring device for lancet-integrated sensor, and cartridge

Apparatus are disclosed for measuring substrate content present in a specimen that is applied to a biosensor, where the apparatus include an input for receiving an electrical signal from the biosensor; and a circuit coupled to the input to detect the electrical signal to determine whether an amount of the specimen needed for specimen detection has been supplied to the biosensor; where the apparatus measures the substrate content included in the specimen when the circuit determines that an amount of the specimen needed for specimen detection has been supplied to the biosensor, and the apparatus is prevented from measuring the substrate content included in the specimen when the circuit determines that the specimen has not been sufficiently supplied to the biosensor.

Methods are disclosed for measuring substrate content in a specimen using a biosensor that includes two pairs of electrodes in a specimen supply path, where the methods include the steps of: (a) a first detecting step for detecting an electrical change in the first pair of electrodes; (b) a second detecting step for detecting an electrical change in the second pair of electrodes after the first detecting step; (c) a judging step for judging a shortage of specimen amount that is needed for measurement, when an electrical change is not detected in the second detecting step within a prescribed period of time after the first detecting step; (d) an indicating step for indicating a shortage of the specimen amount; and (e) a stopping step for stopping measurement of substrate content in the specimen once the shortage of specimen amount is indicated in the indicating step.

Quantifying devices and methods are disclosed for quantifying substrate content using a biosensor where the methods include a first detecting step for detecting an electrical change generated between a measuring electrode and a counter electrode of a biosensor by applying a sample liquid to the biosensor; a second detecting step for detecting an electrical change generated between a detecting electrode of the biosensor and the counter electrode or the measuring electrode by applying the sample liquid to the biosensor; and a notification step for informing a user when the second detecting step does not occur within a predetermined period after the first detecting step.

Measuring device for a lancet-integrated sensor

A biosensor according to the present invention comprises a support, a conductive layercomposed of an electrical conductive material such as noble metal, for example gold, palladium or the like, and carbon, slitsandparallel to the side of the support, slitsandvertical to the side of the support, a working electrode, a counter electrode, a detecting electrode, a spacerwhich covers the working electrode, the counter electrodeand the detecting electrodeon the support, a rectangular cutout partforming a specimen supply path, an inletof the specimen supply path, a reagent layerformed by applying a reagent including an enzyme or the like to the working electrode, the counter electrodeand the detecting electrode, which is exposed from the cutout partof the spacer, and a coverwhich covers the spacer, as shown in FIG. The so-constructed biosensor can be formed by a simple method, and a biosensor which is excellent in a measuring accuracy as well as a biosensor in which a reagent layer is placed uniformly on the electrodes regardless of a reagent liquid composition, and which has a uniform performance can be realized.

Lancet-integrated sensor

Growing community of inventors

Ehime, Japan

Yoshinobu Tokuno