Sbi Pharmaceuticals Co., Ltd.

Yoshinaga Kajimoto

Tohru Tanaka

Masahiro Ishizuka

Toshihiko Kuroiwa

Takahiro Masubuchi

To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) &#x3b4;-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination.RRNCHCOCHCHCOR&#x2003;&#x2003;(1)wherein Rand Reach independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and Rrepresents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.

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Takatsuki, Japan

Yoshinaga Kajimoto