Riken Corporation

Kyowa Kirin Co., Ltd.

Honda Giken Kogyo Kabushiki Kaisha

Yoshimi Yamaguchi

Shigeyuki Yokoyama

Yasuhisa Shiraishi

Kensaku Sakamoto

Akiko Matsumoto

Tatsuo Yanagisawa

Akifumi Kato

Masakazu Homma

Kaname Kimura

Kazumasa Ohtake

Hiroshi Yamaura

Osamu Kudou

Nobuaki Inumaru

Kouichi Tsutsumi

Satoshi Shimashita

The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.

Antibody with non-natural amino acid introduced therein

A lubrication system for an engine includes an oil discharge port in a lower section of a crankcase. A crankshaft, with a crank web attached thereto, rotates in a rotation direction within the crankcase. A first distance is formed between the crank web and a first inner surface of the crankcase, downstream of the oil discharge port. A second distance is formed between the crank web and a second inner surface of the crankcase, upstream of the oil discharge port. The first distance is less than the second distance. Also, the oil discharge port is defined in part by a back edge, which is wedge shaped and points in a direction opposite the rotation direction of the crankshaft. The back edge scoops oil from the crank web and into the oil discharge port.

Lubrication structure for 4-cycle engine

Growing community of inventors

Saitama, Japan

Yoshimi Yamaguchi