Nihon Nohyaku Co., Ltd.

Luke Co., Ltd.

Az, LLC

Az Co., Ltd.

Asamura Patent Office

Salo Pharmaceutical Co., Ltd.

Yoshimi Niwano

Taro Kanno

Keisuke Nakamura

Masanori Yoshida

Minoru Kanno

Hiroyasu Koga

Hiroki Kodama

Kazuo Kanai

Hiroyo Ikai

Masahiro Kono

Hiroaki Kimura

Akira Seo

Kunikazu Hiraga

Kenichi Ikeda

Tsutomu Nishiguchi

Koh Nagasawa

Katsutoshi Endo

Seiji Ishiduka

Masahiro Hayashi

Ryoichi Fukumoto

Hiroyuki Kusakabe

Chong Chu

Satoshi Yanagihara

Chisato Hirosawa

Yoshiyuki Kato

Michihiko Kawaguchi

An aqueous solution for intraoral cleaning via irradiation with ultraviolet ray and/or near-ultraviolet visible ray and/or ray in an 800-900 nm near-infrared region is employed as the hydrogen peroxide aqueous solution, wherein a concentration of hydrogen peroxide is 1 w/v % to 7 w/v %, and a concentration of a hydrogen peroxide stabilizer is 81 ppm (mg/L) or less in the aqueous solution.

Aqueous solution for use in cleaning via irradiation by ultraviolet rays and/or near-ultraviolet visible light and/or light in 800-900 NM near-infrared region, dentifrice including said solution, dental treatment device, toothbrush, and tooth cleaning met

Aqueous solution for use in cleaning via irradiation by ultraviolet rays and/or near-ultraviolet visible light and/or light in 800-900 nm near-infrared region, dentifrice including said solution, dental treatment device, toothbrush, and tooth cleaning method

The purpose of the present invention is to provide a specific wound healing accelerator effective for accelerating healing of wounds, particularly of wounds in the oral cavity, or a composition which includes the wound healing accelerator. This wound healing accelerator including a specific polyphenol is easy to handle and is capable of accelerating would healing even by contact for a short time.

Wound healing accelerator

It is intended to provide a sterilizer, an oral cavity sterilizer, a sterilization method, a sterilization apparatus, and a sterilizer evaluation method capable of enhancing a sterilization effect. The sterilizer including hydrogen peroxide and a catalase activity inhibitor containingor green tea is brought into contact with a sterilization target. Next, the sterilization target is irradiated with light having a wavelength of 350 nm to 500 nm using a light emitting device formed of a semiconductor laser. By the light irradiation, the hydrogen peroxide is photolyzed to generate hydroxy radicals, and sterilization is achieved by the thus-generated hydroxy radicals.

Sterilizer, oral cavity sterilizer, sterilization method, sterilization apparatus, and sterilizer evaluation method

A disinfection method, a disinfection device, and a disinfecting agent which utilizes light, which can achieve a high disinfection effect within a short time are provided. A disinfecting agent containing catechins is brought into contact with an item to be disinfected, and then the disinfecting agent is irradiated with light. The disinfecting agent preferably comprises an aqueous proanthocyanidin solution produced by polymerizing multiple catechin molecules each having a gallate group. Particularly, the aqueous proanthocyanidin solution preferably has a proanthocyanidin concentration of 0.25 to 4 mg/mL. Light with which the disinfecting agent is irradiated preferably has a wavelength of 350 to 500 nm.

Disinfection method and disinfection device

A device includes: a cylindrical first main body having a bottom surface, an inner side surface, and an outer side surface, the first main body having at least one electromagnetic wave irradiation port and at least one antiseptic discharge port, the at least one electromagnetic wave irradiation port being provided in the inner side surface of the first main body, the at least one antiseptic discharge port being provided in the bottom surface and/or the inner side surface of the first main body; an electromagnetic wave generation source; and an antiseptic supply source.

Device for treating peri-implantitis

The present invention provides a 4-oxoquinolizine antibacterial agent having a 2-pyridone skeleton as a partial structure and also having a strong antibacterial effect on gram-positive bacteria, gram-negative bacteria or anaerobic bacteria. The compound having the following formula (I) or a pharmaceutically acceptable salt thereof: wherein:

4-oxoquinolizine antibacterial agent having 2-pyridone skeleton as partial structure

Method for treating mycosis using imidazolylacetonitrile derivatives

A triazole compound or a pharmacologically acceptable salt thereof represented by the following formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are the same or different from each other and each represents a hydrogen atom, a halogen atom or a C.sub.1 -C.sub.6 trihaloalkyl group, R.sub.3 represents a phenyl group which may be substituted or a heterocyclic aromatic ring which may be substituted and X represents S, SO.sub.2 or --(CH.sub.2).sub.n -- where n is 0 or an integer of 1 to 2, excluding a case in which R.sub.1 and R.sub.2 are hydrogen atoms at the same time.

Triazole compound and use thereof

As isothiazole derivative represented by the formula (I), ##STR1## wherein R.sup.1, R.sup.2, Y and Z have the same meanings as defined in the description of the specification, and it is useful as an active ingredient for fungicidal and/or bactericidal compositions for use in industry, agriculture and medical treatment.

Isothiazole derivatives and their uses

Topical compositions are disclosed that comprise a compound represented by formula (I) ##STR1## wherein R.sup.1, R.sup.2 and X are as defined in the specification as an effective ingredient that are effective for accelerating wound healing.

Topical composition for accelerating wound healing

A composition for accelerating healing of a wound is disclosed, comprising as an active ingredient a compound represented by formula (I): ##STR1## wherein R represents a hydrogen atom, a phenyl group or a phenyl group substituted with a halogen atom, a C.sub.1 -C.sub.6 alkyl group, a hydroxyl group or a C.sub.1 -C.sub.6 alkoxy group; and X represents a 1-imidazolyl group or a 1,2,4-triazol-1-yl group.

Composition for accelerating healing of wound

Growing community of inventors

Osakasayama, Japan

Yoshimi Niwano